Visible Light-Induced Synthesis of Sulfenamides via Oxidative Coupling of Amines with Thiols
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 4, 2025
Herein,
we
report
a
visible
light-induced
synthesis
of
sulfenamides
via
the
oxidative
coupling
amines
with
thiols
using
O2
as
an
oxidant.
The
photoreaction
was
conducted
under
simple
and
mild
conditions,
without
any
photocatalysts,
metals,
or
additives.
Detailed
mechanistic
studies
revealed
that
sulfur
radical
is
generated
through
single-electron
transfer
from
in
situ-generated
anion
to
light
irradiation.
This
intermediate
couples
form
disulfide,
which
subsequently
undergoes
aminolysis
produce
sulfenamides.
Язык: Английский
Iodine/DMF-Mediated Regioselective Sulfenylation Using Arenediazonium Tosylates and Sodium Metabisulfite: An Easy Access to 3-Arylthioindoles
Aditya Rai,
Neha Sharma Prabhakar,
Kaushal Kishor
и другие.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(20), С. 15075 - 15082
Опубликована: Окт. 9, 2024
A
practical
C3
sulfenylation
of
indoles
has
been
accomplished
using
arenediazonium
tosylates
and
sodium
metabisulfite,
with
a
key
role
iodine/DMF
combination
in
the
reaction.
The
method
involves
scarce
use
metabisulfite
as
divalent
sulfur
source
offers
an
array
structurally
diverse
3-arylthioindoles
high
yields
under
operationally
simple
transition-metal-free
mild
conditions.
Язык: Английский