Overview of Phenylhydrazine‐Based Organic Transformations DOI Open Access
Pragati Kushwaha,

Ayush Bhardwaj,

Rashi

и другие.

ChemistrySelect, Год журнала: 2024, Номер 10(1)

Опубликована: Дек. 30, 2024

Abstract Phenylhydrazines, comprised of a phenyl group attached with hydrazine unit, contribute potentially to organic synthetic transformations. Because the myriad applications, last decade has witnessed considerable upsurge interest perform various reactions catalyzed/mediated/promoted by phenylhydrazines. Some these have shown high regioselectivity in short reaction time under mild conditions. The emergence innumerable transformations utilizing phenylhydrazine unleashed numerous openings for development diverse heterocyclic scaffolds. Given importance this valuable chemical entity, review highlights methodologies Moreover, present article will considerably synthesis as well pharmaceutical chemistry. Academically, be interesting and informative researchers attempting develop new routes structures.

Язык: Английский

Aryl Borane as a Catalyst for Dehydrative Amide Synthesis DOI

Amit Vinayak Gavit,

Sanjana S. Talekar,

Manoj V. Mane

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 30, 2025

Tris(pentafluorophenyl)borane B(C6F5)3·H2O is reported as a catalyst for dehydrative amidation of carboxylic acids and amines. This protocol applicable across wide range >35 substrates, including aromatic aliphatic amines acids, resulting in amides ≤92% yields. The scalability the reaction up to 10 mmol, along with synthesis drugs such ibuprofen amide, moclobemide, phenacetin, demonstrates industrial potential our protocol.

Язык: Английский

Процитировано

0
Efficient Amidation of Aldehydes and Amine Hydrochloride Salts by Magnetic Cu-MOF Nanocatalyst DOI
Mostafa Ghafori-Gorab,

Hossein Salehi Vanani,

Fatane P. Chegini

и другие.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2025, Номер unknown, С. 136648 - 136648

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Photocatalytic Synthesis of Diaryl Amides via Direct Coupling of Methyl Arenes and Nitroarenes DOI

Robin Prakash Sirvin Rajan,

Chuanshi Hong, Kyung-Ho Park

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

A direct and effective method for synthesizing diaryl amides has been developed through the photocatalytic coupling of methyl nitroarenes. This employs FeCl3 as a redox-active photocatalyst under mild conditions to enable selective benzylic C-H activation concurrent nitro group reduction, eliminating necessity pre-functionalization. exhibits broad substrate scope, high functional tolerance, improved atom economy, offering sustainable practical alternative amide bond formation.

Язык: Английский

Процитировано

0
Overview of Phenylhydrazine‐Based Organic Transformations DOI Open Access
Pragati Kushwaha,

Ayush Bhardwaj,

Rashi

и другие.

ChemistrySelect, Год журнала: 2024, Номер 10(1)

Опубликована: Дек. 30, 2024

Abstract Phenylhydrazines, comprised of a phenyl group attached with hydrazine unit, contribute potentially to organic synthetic transformations. Because the myriad applications, last decade has witnessed considerable upsurge interest perform various reactions catalyzed/mediated/promoted by phenylhydrazines. Some these have shown high regioselectivity in short reaction time under mild conditions. The emergence innumerable transformations utilizing phenylhydrazine unleashed numerous openings for development diverse heterocyclic scaffolds. Given importance this valuable chemical entity, review highlights methodologies Moreover, present article will considerably synthesis as well pharmaceutical chemistry. Academically, be interesting and informative researchers attempting develop new routes structures.

Язык: Английский

Процитировано

0