Recent Progress on Organic Electron Donors (OEDs) Enabled Radical Reactions DOI Open Access
Yu Shao, Xiaodong Jia

Asian Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 21, 2024

Abstract Over the past few decades, organic transformations facilitated by small molecules have witnessed considerable advancements. Small been widely applied to construction of various skeletons. However, reduction as one fundamental reactions is generally initiated metal‐containing reducing agents, although initial progress electron donors (OEDs) enabled reductive cleavage some chemical bonds had achieved in 1990s. Due their structural diversity and tunability, OEDs can overcome limitations metal‐based such low selectivity poor functional group tolerance well environmental problems caused substantial inorganic waste after reactions. Building on a brief historical overview OED research, this review focuses rencent advancements promoted radical It covers C−X (X=C, O, N etc.) single bonds, cyclization, intermolecular addition unsaturated coupling, functionalization aromatics, C−H bond activation. Additionally, mechanistic insights typical are highlighted for understanding reaction mode involving OEDs.

Язык: Английский

Electron-donor-acceptor (EDA) complex-driven regioselective vicinal and oxidative geminal functionalization of alkynes† DOI

Dinabandhu Barik,

Nikita Chakraborty, Ashish Kumar Sahoo

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A visible-light-initiated electron-donor-acceptor (EDA) complex-driven regioselective vicinal and oxidative geminal thiosulfonylation of alkynes is presented. Organic thiosulfonates act as an acceptor, producing either sulfonyl (RSO

Язык: Английский

Процитировано

2
Regio- and Stereoselective β-Sulfonylamination of Alkynes via Photosensitized Bifunctional N–S Bond Homolysis DOI

Tonglv Pu,

Si‐Hai Wu,

Liuyan Cai

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 4, 2024

Nitrogen central radicals (NCRs) are versatile synthetic intermediates for creating functional nitrogen-containing molecules. Herein, a photosensitized β-sulfonylamination of terminal alkynes as well acetylene has been established by employing N-sulfonyl heteroaromatics bifunctional reagents (BFRs) to efficiently deliver (E)-β-sulfonylvinylamines with excellent regio- and stereoselectivities. Mechanistic studies suggest base-accelerated energy transfer (EnT) photocatalysis involving aromatic NCR formation, radical addition alkynes, sulfonylation processes.

Язык: Английский

Процитировано

2
Recent Progress on Organic Electron Donors (OEDs) Enabled Radical Reactions DOI Open Access
Yu Shao, Xiaodong Jia

Asian Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 21, 2024

Abstract Over the past few decades, organic transformations facilitated by small molecules have witnessed considerable advancements. Small been widely applied to construction of various skeletons. However, reduction as one fundamental reactions is generally initiated metal‐containing reducing agents, although initial progress electron donors (OEDs) enabled reductive cleavage some chemical bonds had achieved in 1990s. Due their structural diversity and tunability, OEDs can overcome limitations metal‐based such low selectivity poor functional group tolerance well environmental problems caused substantial inorganic waste after reactions. Building on a brief historical overview OED research, this review focuses rencent advancements promoted radical It covers C−X (X=C, O, N etc.) single bonds, cyclization, intermolecular addition unsaturated coupling, functionalization aromatics, C−H bond activation. Additionally, mechanistic insights typical are highlighted for understanding reaction mode involving OEDs.

Язык: Английский

Процитировано

1