Synthesis of succinyldiamides containing all-quaternary carbon center by photo-induced amidation/smiles rearrangement of alkenes DOI
Yuyu Dai, Wei Niu, Jiapeng Huang

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 23, 2024

A novel, mild, and environmentally friendly method was developed for the synthesis of quaternary-carbon-containing succinyldiamides. This found to be compatible with many substrates.

Язык: Английский

Electron-Donor-Mediated Divergent Transformation of Br–RF via EDA Complex for the Synthesis of Fluorine-Containing Oxindoles and Amides DOI
Shupeng Zhang,

Jin-Xin Lan,

Mei-Ling Yang

и другие.

Organic Letters, Год журнала: 2024, Номер 26(46), С. 9990 - 9995

Опубликована: Ноя. 11, 2024

We have developed an unprecedented electron-donor-controlled divergent reaction between

Язык: Английский

Процитировано

4
Photoinduced Metal‐Free Decarboxylative Fluoroalkylation of Alkenes for the Synthesis of N‐Arylbutanamides and Oxindoles DOI

Yi‐Gang Ji,

Z. Li,

Yuqing Yang

и другие.

Chemistry - A European Journal, Год журнала: 2024, Номер 30(68)

Опубликована: Авг. 28, 2024

The visible light-induced decarboxylative cascade reaction of fluoroalkyl carboxylic acids has been achieved for the efficient synthesis fluorinated compounds. However, most transformations rely on noble iridium metal complex. Herein, a metal-free realized. This protocol features simple operation, transition free, and good functional group tolerance.

Язык: Английский

Процитировано

1
EDA-Enabled Three-Component Polarity-Crossover Cyclization: Modular Installation of Fully Substituted γ-Lactams DOI

Jia-Le Yan,

Zhilin Liu, Kai Chen

и другие.

Organic Letters, Год журнала: 2024, Номер 26(44), С. 9598 - 9603

Опубликована: Окт. 28, 2024

A photoinduced three-component radical addition-aminalization cascade was accomplished, enabling rapid assembly of a wide range densely functionalized γ-lactams. Key to this transformation is the electron-donor-acceptor (EDA) generation enamine and in situ trapping an iminium intermediate with bromodifluoroacetamide. This rationally designed protocol fully takes advantage polarity crossover (enamine-iminium) process, providing modular previously inaccessible scaffolds. The reaction proceeds under mild conditions excellent regio- diastereoselectivity, which amenable structurally varied substrates pharmaceuticals.

Язык: Английский

Процитировано

1
Light-Mediated Direct Decarboxylative Giese Aroylations without a Photocatalyst DOI Creative Commons

David M. Kitcatt,

Eva Pogacar,

Le Mi

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(21), С. 16055 - 16059

Опубликована: Окт. 22, 2024

Previous light-mediated approaches to the direct decarboxylative Giese aroylation reaction have mainly relied on use of a photocatalyst and reductive quenching pathway. By exploiting mechanistically distinct oxidative protocol, we successfully developed photocatalyst-free, methodology.

Язык: Английский

Процитировано

0
Photoinduced Ag-Mediated Azaspirocyclic Approach Involves Cyclization and Dearomatization DOI
Ming Li,

Dong‐Yu Miao,

Fan Gao

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 12, 2024

A visible-light-promoted protocol for azaspirocyclic synthesis from

Язык: Английский

Процитировано

0
Synthesis of succinyldiamides containing all-quaternary carbon center by photo-induced amidation/smiles rearrangement of alkenes DOI
Yuyu Dai, Wei Niu, Jiapeng Huang

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 23, 2024

A novel, mild, and environmentally friendly method was developed for the synthesis of quaternary-carbon-containing succinyldiamides. This found to be compatible with many substrates.

Язык: Английский

Процитировано

0