Trapping in situ generated CF3-nitrile imines with maleimides under solvent-free mechanochemical conditions DOI Creative Commons
Greta Utecht‐Jarzyńska, Szymon Jarzyński, Marcin Jasiński

и другие.

RSC Mechanochemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A series of trifluoromethylated pyrrolo[3,4- c ]pyrazoles were obtained via mechanochemical (3 + 2)-cycloaddition in situ generated trifluoroacetonitrile imines with maleimide and its N -aliphatic/aromatic analogues.

Язык: Английский

Two Faces of Styrylsulfonium Salts: Domino Michael Addition/Cyclopropanation of 2-(2-Acylvinyl)indoles for the Synthesis of Cyclopropa[3,4]pyrrolo[1,2-a]indoles DOI
А.А. Федоров, Danil A. Myasnikov, Elena Y. Mendogralo

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 6, 2025

We report a domino reaction of 2-(2-acylvinyl)indoles as well the corresponding pyrroles with styrylsulfonium salts under mild conditions, affording cyclopropamitosene analogues in high yields and complete diastereoselectivity. A wide range (E)-β-hetaryl-α,β-unsaturated ketones were successfully employed for synthesis potentially bioactive cyclopropa[3,4]pyrrolo[1,2-a]indoles related cyclopropa[a]pyrrolizines, demonstrating versatility developed method. In contrast, (Z)-isomers substrates fail to give derivatives but undergo cyclopropanation terminal methyl group.

Язык: Английский

Процитировано

0
Exercise in 1-aryl-3-CF3-1H-pyrazoles: regioselective synthesis of 4-/5-iodides and cross-coupling reactions DOI Creative Commons

Kamil Świątek,

Greta Utecht‐Jarzyńska, Marcin Jasiński

и другие.

RSC Advances, Год журнала: 2025, Номер 15(12), С. 9225 - 9229

Опубликована: Янв. 1, 2025

A series of 1-aryl-3-CF 3 -1 H -pyrazoles was prepared and examined using iodination reactions.

Язык: Английский

Процитировано

0
Elemental Sulfur/Selenium-Mediated Metal-Free Phosphinothioation and Phosphinoselenoation of Vinylsulfonium Salts with P–H Bonds DOI
Biquan Xiong, Meng Li,

Ruzhen Cao

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 16, 2024

An efficient and facile method has been developed for the construction of novel P–S–C P–Se–C bonds by facilitating three-component cross-coupling reaction P–H with elemental sulfur/selenium vinylsulfonium salts, utilizing sodium bicarbonate as a base. This approach eliminates need use toxic odorous active reagents noble metals, thereby offering new pathway synthesizing S-phosphinothioates Se-phosphinoselenoates via organic conversion inorganic sources. The showcased remarkable versatility in terms substrate applicability, particularly organophosphorus compounds containing salt derivatives. resulting phosphinothioation/phosphinoselenoation products can be obtained high yield regioselectivity. Additionally, plausible mechanism this transformation proposed based on step-by-step control experiments 31P NMR tracking analysis.

Язык: Английский

Процитировано

2
Recent Highlights in the Synthesis and Biological Significance of Pyrazole Derivatives DOI Creative Commons
Ziad Moussa, Mani Ramanathan,

Shaikha Mohammad Alharmoozi

и другие.

Heliyon, Год журнала: 2024, Номер 10(20), С. e38894 - e38894

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

1
Trapping in situ generated CF3-nitrile imines with maleimides under solvent-free mechanochemical conditions DOI Creative Commons
Greta Utecht‐Jarzyńska, Szymon Jarzyński, Marcin Jasiński

и другие.

RSC Mechanochemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A series of trifluoromethylated pyrrolo[3,4- c ]pyrazoles were obtained via mechanochemical (3 + 2)-cycloaddition in situ generated trifluoroacetonitrile imines with maleimide and its N -aliphatic/aromatic analogues.

Язык: Английский

Процитировано

1