Substrate-Induced Cooperative Ionic Catalysis: Difunctionalization of Indole Derivatives Employing Dimethyl Carbonate DOI
Sangita Dattatray Shinde,

Asma Poudel Chhetri,

Sayak Ghosh

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(21), С. 15995 - 16003

Опубликована: Окт. 21, 2024

The global urge to adopt sustainable chemistry has resulted in the development of more environmentally benign strategies (EBS) that use CO2 and CO2-derived chemicals a step-economic manner. In this context, we investigated dual C–H methylation (C═O)-methoxylation indole derivatives using dimethyl carbonate (DMC) presence catalytic amounts Cs2CO3. Mechanistic insights include DMF-assisted, DMC-induced cooperative ionic catalysis, which allows DMC act as both nucleophilic an electrophilic precursor, resulting N-benzylindolyl ketones.

Язык: Английский

Copper-Catalyzed Oxidative Synthesis of 3-Aryl-5-fluoroalkyl-1,3,4-oxadiazol-2(3H)-ones Using Perfluorocarboxylic Anhydride as a Reagent DOI
Jiaqing Lu,

Shouxiong Chen,

Minze Wu

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Сен. 25, 2024

A copper-catalyzed oxidative annulation of sydnones with perfluorocarboxylic anhydride for the synthesis 3-aryl-5-fluoroalkyl-1,3,4-oxadiazol-2(3

Язык: Английский

Процитировано

0
Substrate-Induced Cooperative Ionic Catalysis: Difunctionalization of Indole Derivatives Employing Dimethyl Carbonate DOI
Sangita Dattatray Shinde,

Asma Poudel Chhetri,

Sayak Ghosh

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(21), С. 15995 - 16003

Опубликована: Окт. 21, 2024

The global urge to adopt sustainable chemistry has resulted in the development of more environmentally benign strategies (EBS) that use CO2 and CO2-derived chemicals a step-economic manner. In this context, we investigated dual C–H methylation (C═O)-methoxylation indole derivatives using dimethyl carbonate (DMC) presence catalytic amounts Cs2CO3. Mechanistic insights include DMF-assisted, DMC-induced cooperative ionic catalysis, which allows DMC act as both nucleophilic an electrophilic precursor, resulting N-benzylindolyl ketones.

Язык: Английский

Процитировано

0