Iodine-mediated regioselective C-3 sulfenylation using elemental sulfur and arylhydrazine hydrochloride to access 3-sulfenylated imidazo[1,2-a]pyridines

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер 23(10), С. 2418 - 2423

Опубликована: Янв. 1, 2025

A transition metal-free protocol for the regioselective C-3 sulfenylation of imidazo[1,2-a]pyridines has been explored using arylhydrazine hydrochloride and elemental sulfur, in presence molecular iodine DABCO via C(sp2)-H functionalization to achieve structurally diverse 3-sulfenylated reasonably high yields.

Язык: Английский

I₂‐Promoted Alkylsulfenylation/Cyclization of Enaminones with S‐Alkyl Bunte Salts: Synthesis of 3‐Alkylsulfenylated Chromones

ChemistrySelect, Год журнала: 2025, Номер 10(5)

Опубликована: Фев. 1, 2025

Abstract A novel protocol for effective and efficient synthesis of 3‐alkylsulfenylated chromones in moderate to good yields via I 2 ‐promoted alkylsulfenylation/cyclization enaminones with S ‐alkyl Bunte salts has been described. This reaction features a broad substrate scope, functional group tolerance, metal‐ oxidant‐free conditions.

Язык: Английский