Vicinal diphosphorylation of enaminones with diaryl phosphine oxides via AlCl3-mediated C N bond cleavage DOI
Xin Jin,

An Yong,

Jia Chen

и другие.

Tetrahedron Letters, Год журнала: 2025, Номер 158, С. 155472 - 155472

Опубликована: Фев. 20, 2025

Язык: Английский

Synthesis of Multisubstituted Arylnitriles via Tf2O-Mediated Benzannulation of Enaminones with Acylacetonitriles DOI
Xiaohan Zhang,

Fang Li,

Yue Zhou

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Март 3, 2025

A novel and efficient method for the synthesis of multisubstituted arylnitriles via Tf2O-mediated [3 + 2 1] benzannulation enaminones acylacetonitriles has been developed. This reaction proceeds under mild conditions with excellent functional group compatibility. Mechanistic studies have revealed that cyclization involves two consecutive nucleophilic additions, followed by a cascade Knoevenagel condensation aromatization. Additionally, trifluoromethanesulfonate 6 identified as crucial intermediate in this process.

Язык: Английский

Процитировано

1
Vicinal diphosphorylation of enaminones with diaryl phosphine oxides via AlCl3-mediated C N bond cleavage DOI
Xin Jin,

An Yong,

Jia Chen

и другие.

Tetrahedron Letters, Год журнала: 2025, Номер 158, С. 155472 - 155472

Опубликована: Фев. 20, 2025

Язык: Английский

Процитировано

0