EDA Complex-Mediated Aerobic Three-Component CDC Reactions of Quinoxalinones under Visible-Light Irradiation DOI

Xiaoyuan Wan,

Rui Wen, Yi Fang

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Июнь 2, 2025

A visible-light-induced Minisci-type three-component aerobic cross-dehydrogenative coupling (CDC) reaction of quinoxalinones with styrenes and acetophenones is described. The catalytic electron donor-acceptor (EDA) complexation TMSCl found to be the key for oxygen activation, which initiates oxidative radical formation under photocatalyst-free conditions. This protocol provides facile efficient access structurally valuable highly functionalized generally high chemoselectivity moderate good yields.

Язык: Английский

Intermolecular amination of Ethyl Benzo ylacetate via photocatalytic nitrene transfer reactions DOI
Yujing Guo, Yifan Guo,

Luyao Ding

и другие.

Organic Chemistry Frontiers, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

This study reports a photocatalytic nitrene transfer reaction of 1,3-dicarbonyl. A broad range substrates and iodinanes are shown, enabling direct C–H functionalization without the need for pre-formed nucleophilic enolate equivalents.

Язык: Английский

Процитировано

0

g-C3N4-Based Heterogeneous Photocatalyzed Synthesis and Evaluation of Antitumor Activities of Fluoroalkylated 4H-Pyrido[1,2-a]pyrimidin-4-ones DOI
Ningbo Li, Yan Liu,

Chu-Qian Hu

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 26, 2025

The first example of heterogeneous photoredox-catalyzed fluoroalkylation 4H-pyrido[1,2-a]pyrimidin-4-ones has been developed. With low-cost commercial g-C3N4 as the recyclable photocatalyst and cheap sodium fluoroalkyl sulfonates source, a variety fluoroalkylated pyridopyrimidinones were constructed in moderate to high yields. present reaction can be easily scaled up with good efficiency, catalytic system reused 5 times slight loss activities. Furthermore, biological activity synthesized compounds was preliminarily investigated.

Язык: Английский

Процитировано

0

Visible‐Light‐Induced C−H Amidation of (Hetero)arenes with Hypervalent Iodine(III) Reagents DOI Open Access
Xiaojuan Wang, He Wang, Zhenkun Ma

и другие.

Asian Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Abstract A visible‐light‐promoted C−H amidation of (hetero)arenes with hypervalent iodine reagents has been successfully achieved good yields. The high efficiency, broad substrate range and functional group compatibility demonstrated the utility method. Moreover, this protocol was suitable for late‐stage functionalization natural products. Mechanistic studies have shown that N‐centred saccharin radical mediates arenes.

Язык: Английский

Процитировано

0

visible light-induced recyclable g-C3N4 catalyzed C-H/N-H cross-dehydrogenative coupling amination of Quinoxalin-2(1H)-ones DOI

Zongjie Ma,

Linzhao Li,

Gaoli Chen

и другие.

Tetrahedron, Год журнала: 2025, Номер unknown, С. 134707 - 134707

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

AgOTf‐Catalysed Regioselective C1‐Amination of Pyrrolo[1,2‐a]quinoxaline With Azodicarboxylates DOI
Wanqiang Wang, Jing Guo,

Di Hao

и другие.

Applied Organometallic Chemistry, Год журнала: 2025, Номер 39(6)

Опубликована: Май 19, 2025

ABSTRACT AgOTf‐catalysed regioselective C1‐amination of pyrrolo[1,2‐ a ]quinoxaline has been developed. The reaction allowed the use various ]quinoxalines and azodicarboxylates as coupling partners to afford C1‐aminated products with good excellent yields. synthetic strategy showed regioselectivity, functional group tolerance well gram‐scale synthesis. amination were further modified furnish structurally diverse compounds.

Язык: Английский

Процитировано

0

Recent Advances in Photo-promoted Generalized C3-H Alkylation of Quinoxalin-2(1H)-ones DOI
Youpeng Zuo, Xu Bai, Cong Wang

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Recent advances in the photo-promoted C3–H alkylation reaction of quinoxalin-2(1 H )-ones with different agents.

Язык: Английский

Процитировано

0

Photoinduced β-fragmentation for efficient pyridine alkylation via N-alkoxypyridinium salts DOI
Heng Liu, Fangrui Wu,

Zhidong Wan

и другие.

Organic Chemistry Frontiers, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

We established a mild and atom-economical photocatalytic strategy for direct pyridine alkylation via β-fragmentation of N -alkoxypyridinium salts, serving dually as alkyl radical precursors sources.

Язык: Английский

Процитировано

0

Nd@g-C3N4 dual-functional photosynthesis and antitumor activities of 3-fluoroalkylated quinoxalin-2(1H)-ones DOI

Qiong-Hui Peng,

Ningbo Li,

Jia-Cheng Hou

и другие.

Chinese Chemical Letters, Год журнала: 2025, Номер unknown, С. 111402 - 111402

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

EDA Complex-Mediated Aerobic Three-Component CDC Reactions of Quinoxalinones under Visible-Light Irradiation DOI

Xiaoyuan Wan,

Rui Wen, Yi Fang

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Июнь 2, 2025

A visible-light-induced Minisci-type three-component aerobic cross-dehydrogenative coupling (CDC) reaction of quinoxalinones with styrenes and acetophenones is described. The catalytic electron donor-acceptor (EDA) complexation TMSCl found to be the key for oxygen activation, which initiates oxidative radical formation under photocatalyst-free conditions. This protocol provides facile efficient access structurally valuable highly functionalized generally high chemoselectivity moderate good yields.

Язык: Английский

Процитировано

0