The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 13, 2025

The fascinating skeleton 3,2′-pyrrolidinyl spirooxindole exhibits diverse pharmacological activity. Despite advancements in the construction of this skeleton, application rearrangement strategy for synthesis remains underexplored. Herein, we reported an efficient method by [2,3]-rearrangement reaction between 3-diazoindolin-2-one and arecoline under mild conditions, which had a good functional group tolerance high yield. This work not only facilitates study selective ammonium ylide but also contributes significantly to spiro compounds.

Язык: Английский