Advanced Synthesis & Catalysis,
Год журнала:
2019,
Номер
362(4), С. 877 - 883
Опубликована: Дек. 14, 2019
Abstract
The
novel
free
radical‐based
cleavage
of
the
enaminone
C=C
double
bond
is
realized
by
using
N
‐halosuccinimides
(NXS)
in
presence
benzoyl
peroxide
(BPO)
with
mild
heating,
enabling
tunable
synthesis
α,α‐dihalomethyl
ketones
and
α,α,α‐trihalomethyl
under
different
reaction
conditions.
formation
these
divergent
products
involving
featured
requires
no
any
metal
reagent,
represents
one
more
practical
example
on
poly
halogenated
methyl
via
functionalization
carbon−carbon
bond.
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image
Biomedicines,
Год журнала:
2022,
Номер
10(5), С. 1124 - 1124
Опубликована: Май 12, 2022
Pyrazoles
are
five-membered
heterocyclic
compounds
that
contain
nitrogen.
They
an
important
class
of
for
drug
development;
thus,
they
have
attracted
much
attention.
In
the
meantime,
pyrazole
derivatives
been
synthesized
as
target
structures
and
demonstrated
numerous
biological
activities
such
antituberculosis,
antimicrobial,
antifungal,
anti-inflammatory.
This
review
summarizes
results
published
research
on
synthesis
activities.
The
works
between
January
2018
December
2021
were
retrieved
from
Scopus
database
reviewed
accordingly.
Advanced Synthesis & Catalysis,
Год журнала:
2022,
Номер
364(9), С. 1508 - 1521
Опубликована: Апрель 8, 2022
Abstract
Enaminones
have
in
the
past
decade
received
renewed
interest
organic
synthesis
by
acting
as
highly
versatile
building
blocks.
Particularly,
featured
amino
and
carbonyl
group
enaminone
structure
endow
them
with
ability
of
tolerating
water
via
hydrogen
bonding
effect.
Thus,
designing
synthetic
methods
aqueous
medium
enaminones
main
blocks
has
extensive
attention
notable
success.
Based
on
our
longstanding
efforts
interests
chemistry,
we
review
herein
research
advances
participated
medium.
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image
ACS Omega,
Год журнала:
2022,
Номер
7(42), С. 36945 - 36987
Опубликована: Окт. 10, 2022
1,2,3-Triazole
scaffolds
are
not
obtained
in
nature,
but
they
still
intensely
investigated
by
synthetic
chemists
various
fields
due
to
their
excellent
properties
and
green
routes.
This
review
will
provide
a
library
of
all
routes
used
the
past
21
years
synthesize
1,2,3-triazoles
derivatives
using
metal
catalysts
(such
as
Cu,
Ni,
Ru,
Ir,
Rh,
Pd,
Au,
Ag,
Zn,
Sm),
organocatalysts,
metal-free
well
solvent-
catalyst-free
neat
syntheses,
along
with
mechanistic
cycles,
recyclability
studies,
solvent
systems,
reaction
condition
effects
on
regioselectivity.
Constant
developments
indicate
that
help
lead
future
organic
synthesis
useful
for
creating
molecular
libraries
functionalized
1,2,3-triazoles.
Organic & Biomolecular Chemistry,
Год журнала:
2022,
Номер
20(12), С. 2356 - 2369
Опубликована: Янв. 1, 2022
Enaminones
and
analogous
stable
enamines
are
well
known
as
platform
building
blocks
in
organic
synthesis
for
the
construction
of
heterocyclic
compounds,
especially
N-heterocycles.
To
date,
enaminones
have
been
successfully
employed
various
5-
or
6-
membered
heterocycles.
Recently,
synthetic
protocols
accomplished
by
diversity-oriented
annulation
reactions
based
on
C-N
bond
cleavage
gained
notable
success.
In
this
review,
development
transition
metal-free
product
featuring
a
is
reviewed.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
362(17), С. 3516 - 3541
Опубликована: Июнь 11, 2020
Abstract
Sulfonyl
hydrazides
are
widely
used
as
organic
reagents.
Advances
in
the
past
decade
summarized
following
categories
by
key
intermediates:
(1)
[RO
2
S
.
];
(2)
RO
SSR;
(3)
[ArS
(4)
−
(5)
RSO
‐[Metal]
species;
(6)
Ar‐[Metal]
(7)
RSX;
(8)
RS‐DBU;
(9)
nucleophilic
amino
group;
(10)
sulfonyl
diazene
or
sulfinic
acid
surrogate.
Reactions
with
alkenes,
alkynes,
aldehydes,
alcohols,
thiophenol,
Grignard
reagents,
among
others,
discussed.
We
hope
this
review
will
promote
future
research
area.
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image
ChemistrySelect,
Год журнала:
2020,
Номер
5(42), С. 13103 - 13134
Опубликована: Ноя. 13, 2020
Abstract
Sodium
sulfinates,
sulfinic
acids,
sulfonyl
chlorides
and
hydrazides
as
readily
available
efficient
sulfonylation
reagents
have
been
extensively
explored
in
recent
years.
Sulfonyl
radical
can
be
generated
from
these
via
different
methods,
then
the
could
react
with
various
substrates
pathways
to
afford
corresponding
products.
In
this
review,
we
will
summarize
progress
reaction
using
sodium
three
terms
of
reagents,
classify
reactions
into
four
types:
1.
Sulfonylation
sulfinates.
2.
acid.
3.
chlorides.
4.
hydrazides.
Advanced Synthesis & Catalysis,
Год журнала:
2020,
Номер
362(21), С. 4579 - 4654
Опубликована: Авг. 3, 2020
Abstract
Oxidative
coupling
methodology
is
widely
applied
for
the
formation
of
carbon‐carbon
and
carbon‐heteroatom
bonds.
This
review
focuses
on
methods
oxidative
sulfonylation
multiple
bonds
involving
sulfonyl
hydrazides,
sulfinic
acids
their
salts
as
reagents.
Under
conditions,
they
generate
radicals,
trapped
by
resulting
in
a
variety
SO
2
‐containing
products:
mainly,
vinyl
alkynyl
sulfones,
hydroxy‐,
keto,
halo‐substituted
sulfonylated
derivatives
carbo‐
heterocycles.
exhaustive
summarizes
321
references
from
1996
to
2020
with
specialization
studies
last
five
years,
divided
into
chapters
according
classes
compounds
being
sulfonylated.
magnified
image
Organic Chemistry Frontiers,
Год журнала:
2020,
Номер
7(18), С. 2770 - 2775
Опубликована: Янв. 1, 2020
The
synthesis
of
3-trifluoromethyl
chromones
has
been
realized
via
transition
metal-free
reactions
o-hydroxyphenyl
enaminones
and
the
Langlois
reagent
cascade
C–H
trifluoromethylation
chromone
annulation.
Green Chemistry,
Год журнала:
2019,
Номер
22(1), С. 118 - 122
Опубликована: Ноя. 29, 2019
A
practical
method
for
the
clean
preparation
of
multisubstituted
pyrroles
via
an
iodine-catalyzed
multicomponent
reaction
under
metal-
and
solvent-free
conditions
was
developed.
In
gram-scale
synthesis,
can
be
easily
collected
through
simple
extraction.
