Structural and therapeutic properties of salicylic acid-solubilized Pluronic solutions and hydrogels
Soft Matter,
Год журнала:
2024,
Номер
20(9), С. 2075 - 2087
Опубликована: Янв. 1, 2024
Salicylic
acid
(SA)
finds
extensive
applications
in
the
treatment
of
rheumatic
and
skin
diseases
because
its
analgesic,
anti-inflammatory
exfoliating
properties.
Язык: Английский
Probing Interparticle Interaction and Ordering in Silica–Pluronic-Based Solutions and Emulsions by Small-Angle Scattering Techniques
The Journal of Physical Chemistry B,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 9, 2025
Introduction
of
non-DLVO
forces
by
nonionic
surfactants
brings
about
fascinating
changes
in
the
phase
behavior
silica
nanosuspensions.
We
show
here
that
alterations
interaction
and
wetting
properties
negatively
charged
nanoparticles
(Ludox®
LS)
presence
polyethylene
oxide–polypropylene
oxide–polyethylene
oxide-based
triblock
copolymers
called
Pluronics
lead
to
formation
stable
o/w
Pickering
emulsions
interparticle
attraction-induced
thermoresponsive
liquid–liquid
separations.
The
results
make
interesting
comparisons
with
those
reported
for
Ludox®
TM
nanosuspensions
comprising
larger
nanoparticles.
Association
these
nanosystems
occurs
through
their
surface
silanol
groups.
LS
a
higher
surface-to-volume
ratio
thus
need
amount
onset
attraction
as
compared
counterparts.
Small-angle
X-ray
scattering
studies
reveal
unlike
nanosuspensions,
form
ordering
both
Pluronic-coated
bare
at
oil–water
interface.
This
could
arise
due
steric
limitations
accommodating
large
Pluronic
molecules
between
smaller
nanoparticles,
highly
curved
surfaces,
closed-packed
configurations.
Small
angle
neutron
clear
signatures
intermicellar
systems
function
temperature
concentration,
induced
solely
modulation
hydrophobic
interactions,
not
hitherto
give
insights
into
roles
hydrophilic–lipophilic
balance
size
determining
behaviors
silica–surfactant
nanocomposite
systems.
Язык: Английский
Interaction of vascular endothelial cells with hydrophilic fullerene nanoarchitectured structures in 2D and 3D environments
Science and Technology of Advanced Materials,
Год журнала:
2024,
Номер
25(1)
Опубликована: Фев. 13, 2024
The
interaction
between
diverse
nanoarchitectured
fullerenes
and
cells
is
crucial
for
biomedical
applications.
Here,
we
detailed
the
preparation
of
hydrophilic
self-assembled
by
liquid-liquid
interfacial
precipitation
(LLIP)
method
coating
materials
as
a
possible
vascularization
strategy.
interactions
vascular
endothelial
(ECs)
with
fullerene
nanotubes
(FNT-P)
nanowhiskers
(FNW-P)
were
investigated.
average
length
diameter
FNT-P
16
±
2
μm
3.4
0.4
(i.e.
aspect
ratios
4.6),
respectively.
FNW-P
65
8
1.2
0.2
53.9),
For
two-dimensional
(2D)
culture
after
7
days,
ECs
remained
viable
proliferated
up
to
~
420%
400%
50
μg/mL,
Furthermore,
an
optimized
chitosan-based
self-healing
hydrogel
modulus
~400
Pa
was
developed
used
incorporate
in
vitro
three-dimensional
(3D)
platforms
investigate
impact
on
within
3D
environment.
addition
or
(50
μg/mL)
system
led
proliferation
rates
323%
280%,
respectively,
days
culture.
displayed
elongated
shape
aligned
morphology,
while
those
exhibited
rounded
clustered
distribution.
Vascular-related
gene
expressions
significantly
upregulated
through
these
fullerenes.
Thus,
combined
use
different
hydrogels
may
offer
environmental
cues
influencing
EC
development
biomimetic
microenvironment,
holding
promise
advancing
strategy
tissue
engineering.
Язык: Английский
Interfacial Behavior of Biodegradable Poly(lactic-co-glycolic acid)-Pluronic F127 Nanoparticles and Its Impact on Pickering Emulsion Stability
Langmuir,
Год журнала:
2024,
Номер
40(24), С. 12353 - 12367
Опубликована: Июнь 7, 2024
Biodegradable
nanoparticle-based
emulsions
exhibit
immense
potential
in
various
applications,
particularly
the
pharmaceutical,
cosmetic,
and
food
industries.
This
study
delves
into
intricate
interfacial
behavior
of
Pluronic
F127
modified
poly(lactic-co-glycolic
acid)
(PLGA-F127)
nanoparticles,
a
crucial
determinant
their
ability
to
stabilize
Pickering
emulsions.
Employing
combination
Langmuir
balance,
surface
tension,
diffusion
coefficient
measurements,
we
investigate
dynamics
PLGA-F127
nanoparticles
under
varying
temperature
ionic
strength
conditions.
Theoretical
calculations
are
employed
elucidate
underlying
mechanisms
governing
these
phenomena.
Our
findings
reveal
profound
influence
temperature-dependent
layer
electrostatic
steric
interactions
on
dynamics.
Nonlinear
changes
tension
observed,
reflecting
interplay
factors.
Particle
aggregation
is
found
be
prevalent
at
elevated
temperatures
strengths,
compromising
stability
emulsification
efficiency
formed
work
provides
insights
rational
design
stable
efficient
biodegradable
emulsions,
broadening
applications
fields.
Язык: Английский
Competing Effects of Temperature and Polymer Concentration on Evolution of Re-entrant Interactions in the Nanoparticle-Block Copolymer System
Langmuir,
Год журнала:
2024,
Номер
40(29), С. 14888 - 14899
Опубликована: Июль 8, 2024
An
interesting
evolution
of
the
re-entrant
interaction
has
been
observed
in
an
anionic
silica
nanoparticle
(NP)-block
copolymer
(P85)
dispersion
due
to
mutually
competing
effects
temperature
and
polymer
concentration.
It
demonstrated
that
a
rise
leads
attraction
system,
which
interestingly
diminishes
on
increasing
Consequently,
system
exhibits
transition
from
repulsive
attractive
back
at
given
but
with
respect
concentration,
within
selected
region
concentration
temperature.
The
intriguing
observations
have
elucidated
based
temperature/concentration-dependent
modifications
interactions
governing
as
probed
by
contrast-variation
small-angle
neutron
scattering.
initial
is
attributed
temperature-driven
enhancement
hydrophobicity
amphiphilic
triblock
adsorbed
nanoparticles.
strength
range
this
are
found
be
more
than
van
der
Waals
while
relatively
less
electrostatic
interaction.
At
higher
concentrations,
saturation
adsorption
nanoparticles
introduces
additional
steric
repulsion
along
between
their
conjugates,
effectively
reducing
attraction.
However,
significant
increase
(>75
°C),
again
dominates
eventually
particle
aggregation
all
measured
concentrations
(>0.1
wt
%).
Our
study
provides
useful
inputs
develop
smart
NP-polymer
composites
having
capabilities
respond
external
stimuli
such
temperature/concentration
variation.
Язык: Английский
Adsorption of Mixed Dispersions of Silica Nanoparticles and an Amphiphilic Triblock Copolymer at the Water–Vapor Interface
Applied Sciences,
Год журнала:
2023,
Номер
13(18), С. 10093 - 10093
Опубликована: Сен. 7, 2023
This
study
investigates
the
surface
modification
of
hydrophilic
silica
nanoparticles
by
non-chemical
adsorption
an
amphiphilic
triblock
copolymer,
Pluronic
F-127,
and
elucidates
its
influence
on
interfacial
dispersion
properties.
The
interaction
between
F-127
drives
formation
copolymer-decorated
particles
with
increased
hydrodynamic
diameter
reduced
effective
charge
as
copolymer
concentration
increases,
while
opposite
effect
occurs
particle
increases
at
a
fixed
polymer
concentration.
indicates
that
increasing
leads
to
increase
in
coating
density,
whereas
decrease.
is
paramount
importance
for
modulating
reorganization
shell
upon
fluid–fluid
interfaces
and,
thus,
decorated
interface
rheological
properties
obtained
layers.
In
fact,
relationship
tension,
well
mechanical
response
interface,
mirrors
patterns
observed
solutions,
only
shift
mediated
found.
suggests
presence
limits
space
available
molecules
reorganize
but
does
not
significantly
affect
behavior
particle-laden
interface.
Язык: Английский