Cyclized/Knotted Polydivinylbenzene (Pdvb) Antibacterial Coatings
Опубликована: Янв. 1, 2025
In
the
medical
industry,
minimizing
biofouling
is
of
utmost
importance
as
it
helps
to
reduce
bacterial
adhesion
and
prevent
cross-infection.
this
study,
cyclized/knotted
polydivinylbenzene
(PDVB),
a
polymer
with
distinctive
structural
features,
proposed
for
first
time
be
utilized
in
preparation
antibacterial
coatings.
Firstly,
(PDVB)
synthesized
via
deactivation-enhanced
atom
transfer
radical
polymerization
(DE-ATRP).
Subsequently,
processed
into
coatings
by
employing
"grafting
to"
method.
The
obtained
PDVB
display
remarkable
activity
on
both
glass
titanium
alloy
substrates
owing
their
unique
structure,
effectively
inhibiting
proliferation
common
pathogenic
bacteria.
Additionally,
also
exhibit
excellent
hydrophobicity,
strong
adhesion,
superior
thermal
stability.
These
research
findings
suggest
that
possess
outstanding
physicochemical
properties
demonstrate
powerful
performance.
It
anticipated
open
up
new
avenues
materials.
Язык: Английский
Cyclized/knotted Polydivinylbenzene (PDVB) antibacterial coatings
Progress in Organic Coatings,
Год журнала:
2025,
Номер
205, С. 109304 - 109304
Опубликована: Апрель 10, 2025
Язык: Английский
Biobased Cyclic Polycarbonate: Synthesis and Applications via Dynamic Bis(hindered amino)disulfide Linkers
ACS Macro Letters,
Год журнала:
2025,
Номер
unknown, С. 750 - 756
Опубликована: Май 17, 2025
Cyclic
polymers
have
garnered
significant
interest
due
to
their
unique
structure;
however,
synthesis
remains
challenging,
often
hindered
by
low
yields
and
limited
selectivity.
Considering
that
the
cyclization
step
during
of
cyclic
is
presumably
most
using
a
spontaneous
selective
system
ideal.
Here,
we
present
topology
transformation
from
linear
cyclic,
which
achieved
through
error-checking
ability
provided
dynamic
covalent
bonding
between
bis(2,2,6,6-tetramethylpiperidin-1-yl)disulfide
(BiTEMPS)
its
stable
radicals
with
high
bond
exchange
rate.
When
applying
this
method
biobased
poly(isosorbide
carbonate)
(PIC),
an
attractive
alternative
conventional
petroleum-based
polycarbonates,
high-molecular-weight
were
unexpectedly
obtained.
Since
functionalization
PICs
has
been
traditionally
copolymerization
techniques,
aimed
introduce
bonds
establish
novel
methods
for
PICs.
Interestingly,
intramolecular
in
heterogeneous
proceeded
via
ring-expansion
polymerization-like
mechanism,
affording
consisting
PIC
backbone
BiTEMPS
units
as
units.
The
resulting
PIC-based
applied
reactions,
providing
effective
approach
block
end-functionalized
skeleton.
These
results
demonstrate
potential
chemistry
polymer
synthesis.
Язык: Английский
Novel All-Polymer Nanocomposites Enable Manipulation of Mechanical Properties via Self-Assembly
Macromolecules,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 18, 2025
Язык: Английский
Efficient Cytosolic Delivery of Single-Chain Polymeric Artificial Enzymes for Intracellular Catalysis and Chemo-Dynamic Therapy
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
147(1), С. 998 - 1007
Опубликована: Дек. 30, 2024
Designing
artificial
enzymes
for
in
vivo
catalysis
presents
a
great
challenge
due
to
biomacromolecule
contamination,
poor
biodistribution,
and
insufficient
substrate
interaction.
Herein,
we
developed
single-chain
polymeric
nanoparticles
with
Cu/N-heterocyclic
carbene
active
sites
(SCNP-Cu)
function
as
peroxidase
mimics
chemo-dynamic
therapy
(CDT).
Compared
the
enzyme
based
on
unfolded
linear
polymer
scaffold
multichain
cross-linked
scaffold,
SCNP-Cu
exhibits
improved
tumor
accumulation
CDT
efficiency
both
vitro
vivo.
Protein-like
size
of
SCNP
promotes
passive
diffusion,
whereas
positive
surface
charge
allows
its
transcytosis
deep
penetration
hence
site.
The
submolecular
compartments
effectively
protect
from
protein
bindings,
thereby
providing
"cleaner"
microenvironment
within
living
system.
folded
structure
facilitates
their
cytosolic
delivery
free
diffusion
cytosol,
ensuring
efficient
contact
endogenous
H2O2,
situ
generation
toxic
hydroxyl
radicals
(·OH),
effective
damage
intracellular
targets
(i.e.,
lipids,
nucleic
acids).
This
work
establishes
versatile
SCNP-based
nanoplatforms
developing
catalysis.
Язык: Английский