Опубликована: Янв. 1, 2024
Язык: Английский
Sustainable Chemistry and Pharmacy, Год журнала: 2025, Номер 45, С. 101988 - 101988
Опубликована: Март 14, 2025
Язык: Английский
Процитировано
0
Angewandte Chemie International Edition, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 29, 2024
Abstract Photomediated Atom Transfer Radical Polymerization (photoATRP) is an activator regeneration method, which allows for the controlled synthesis of well‐defined polymers via light irradiation. Traditional photoATRP often limited by need high‐energy ultraviolet or violet light. These could negatively affect control and selectivity polymerization, promote side reactions, may not be applicable to biologically relevant systems. This drawback can circumvented introduction catalytic amount photocatalysts, absorb visible and/or NIR and, therefore, controlled, regenerative ATRP performed with dual‐catalytic cycle. Herein, a critical summary recent developments in field dual‐catalysis concerning Cu‐catalyzed provided. Contributions involved species are examined mechanistically, followed challenges future directions towards next generation advanced functional macromolecular materials.
Язык: Английский
Процитировано
2
Polymer Chemistry, Год журнала: 2024, Номер 15(41), С. 4264 - 4280
Опубликована: Янв. 1, 2024
Heterogeneous photocatalysts (PCs) have garnered attention for their sustainability and cost-effectiveness.
Язык: Английский
Процитировано
1
Biomacromolecules, Год журнала: 2024, Номер 25(11), С. 7433 - 7445
Опубликована: Окт. 18, 2024
This study explores the synthesis and application of artificial zymogens using protein-polymer hybrids to mimic controlled enzyme activation observed in natural zymogens. Pro-trypsin (pro-TR) pro-chymotrypsin (pro-CT) were engineered by modifying surfaces trypsin (TR) chymotrypsin (CT) with cleavable peptide inhibitors utilizing surface-initiated atom transfer radical polymerization. These exhibited 70 90% reductions catalytic efficiency for pro-TR pro-CT, respectively, due inhibitory effect grafted inhibitors. The CT pro-CT TR resulted 1.5- 2.5-fold increases enzymatic activity, respectively. Furthermore, activated triggered an cascade, enabling amplification activity through a dual pro-protease hybrid system. highlights potential therapeutic interventions biodetection platforms harnessing cascades precise control activity.
Язык: Английский
Процитировано
1
Polymer, Год журнала: 2024, Номер 312, С. 127620 - 127620
Опубликована: Сен. 11, 2024
Язык: Английский
Процитировано
0
Angewandte Chemie, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 29, 2024
Abstract Photomediated Atom Transfer Radical Polymerization (photoATRP) is an activator regeneration method, which allows for the controlled synthesis of well‐defined polymers via light irradiation. Traditional photoATRP often limited by need high‐energy ultraviolet or violet light. These could negatively affect control and selectivity polymerization, promote side reactions, may not be applicable to biologically relevant systems. This drawback can circumvented introduction catalytic amount photocatalysts, absorb visible and/or NIR and, therefore, controlled, regenerative ATRP performed with dual‐catalytic cycle. Herein, a critical summary recent developments in field dual‐catalysis concerning Cu‐catalyzed provided. Contributions involved species are examined mechanistically, followed challenges future directions towards next generation advanced functional macromolecular materials.
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0