Towards cell-adhesive, 4D printable PCL Networks through dynamic covalent chemistry DOI
Sagnik Ghosh, Sathiyaraj Subramaniyan,

Anadi Bisht

и другие.

Journal of Materials Chemistry B, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

In recent years, the development of biodegradable, cell-adhesive polymeric implants and minimally invasive surgery has significantly advanced healthcare. These materials exhibit multifunctional properties like self-healing, shape-memory, cell adhesion, which can be achieved through novel chemical approaches. Engineering such their scalability using a classical polymer network without complex synthesis modification been great challenge, potentially resolved biobased dynamic covalent chemistry (DCC). Here, we report scalable, self-healable, poly(ε-caprolactone) (PCL)-based vitrimer scaffold, imine exchange, free from limitations melting transitions supramolecular interactions in 4D-printed PCL. PCL's typical hydrophobicity hinders adhesion; however, our design, based on photopolymerization PCL-dimethacrylate methacrylate-terminated vanillin-based imine, achieves water contact angle 64°. The network, fabricated varying proportions, exhibited co-continuous phase morphology, achieving optimal shape fixity (91 ± 1.7%) recovery (92.5 0.1%) at physiological temperature (37 °C). Additionally, scaffold promoted adhesion proliferation reduced oxidative stress defect site. This material shows potential DCC-based research developing smart biomedical devices with geometries, paving way for applications regenerative medicine implant design.

Язык: Английский

Dynamic Covalent Polymer Networks: A Molecular Platform for Designing Functions beyond Chemical Recycling and Self-Healing DOI
Ning Zheng, Yang Xu, Qian Zhao

и другие.

Chemical Reviews, Год журнала: 2021, Номер 121(3), С. 1716 - 1745

Опубликована: Янв. 4, 2021

Dynamic covalent polymer networks (DCPN) have historically attracted attention for their unique roles in chemical recycling and self-healing, which are both relevant sustainable societal development. Efforts these directions intensified the past decade with notable progress newly discovered dynamic chemistry, fundamental material concepts, extension toward emerging applications including energy electronic devices. Beyond that, values of DCPN discovering/designing functional properties not offered by classical thermoplastic thermoset polymers recently gained traction. In particular, bond exchangeability has shown unparalleled design versatility various areas shape-shifting materials/devices, artificial muscles, microfabrication. Going beyond this basic exchangeability, molecular mechanisms to manipulate network topologies (topological transformation) led opportunities program polymers, concepts such as living topological isomerization. review, we provide an overview above particular focuses on strategies exploitation properties. Based this, point out remaining issues offer perspectives how class materials can shape future ways that complementary polymers.

Язык: Английский

Процитировано

932

Vitrimers: directing chemical reactivity to control material properties DOI Creative Commons
Marc Guerre, Christian Taplan, Johan M. Winne

и другие.

Chemical Science, Год журнала: 2020, Номер 11(19), С. 4855 - 4870

Опубликована: Янв. 1, 2020

In this minireview, we survey recent advances in the development of vitrimer materials. Focus on how to chemically control their material properties is used highlight challenges for boosting potential emerging class polymer

Язык: Английский

Процитировано

463

Intrinsically Self-Healing Polymers: From Mechanistic Insight to Current Challenges DOI
Bingrui Li, Pengfei Cao, Tomonori Saito

и другие.

Chemical Reviews, Год журнала: 2022, Номер 123(2), С. 701 - 735

Опубликована: Дек. 28, 2022

Self-healing materials open new prospects for more sustainable technologies with improved material performance and devices' longevity. We present an overview of the recent developments in field intrinsically self-healing polymers, broad class based mostly on polymers dynamic covalent noncovalent bonds. describe current models mechanisms discuss several examples systems different types bonds, from various hydrogen bonds to The advances indicate that most intriguing results are obtained have combined These demonstrate high toughness along a relatively fast rate. There is clear trade-off relationship between rate mechanical modulus materials, we propose design principles toward surpassing this trade-off. also applications summarize challenges field. This review intends provide guidance intrinsic required properties.

Язык: Английский

Процитировано

294

Reprocessable Cross-Linked Polymer Networks: Are Associative Exchange Mechanisms Desirable? DOI Creative Commons
Benjamin R. Elling, William R. Dichtel

ACS Central Science, Год журнала: 2020, Номер 6(9), С. 1488 - 1496

Опубликована: Июль 29, 2020

Covalent adaptable networks (CANs) are covalently cross-linked polymers that may be reshaped via cross-linking and/or strand exchange at elevated temperatures. They represent an exciting and rapidly developing frontier in polymer science for their potential as stimuli-responsive materials to make traditionally nonrecyclable thermosets more sustainable. CANs whose cross-links undergo associative intermediates rather than dissociating separate reactive groups termed vitrimers. Vitrimers were postulated attractive subset of CANs, because cross-link mechanisms maintain the original density network throughout process. As a result, demonstrate gradual, Arrhenius-like reduction viscosity temperatures while maintaining mechanical integrity. In contrast, reprocessed by dissociation reformation have been exhibit rapid decrease with increasing temperature. Here, we survey stress relaxation behavior all dissociative which variable temperature or data reported date. All Arrhenius relationship between viscosity, only small percentage broken instantaneously under typical reprocessing conditions. such, show nearly identical over broad ranges typically used reprocessing. Given term vitrimer was coined highlight temperature, analogy vitreous glasses, discourage its continued use describe CANs. The realization mechanism does not greatly influence practical most suggests chemistries can considered fewer constraints, focusing instead on activation parameters, synthetic convenience, application-specific considerations.

Язык: Английский

Процитировано

288

Vitrimers: Current research trends and their emerging applications DOI Creative Commons
Jie Zheng, Zhuang Mao Png, Shi Hoe Ng

и другие.

Materials Today, Год журнала: 2021, Номер 51, С. 586 - 625

Опубликована: Июль 29, 2021

Язык: Английский

Процитировано

284

Healable and self-healing polyurethanes using dynamic chemistry DOI
Robert Aguirresarobe,

Sil Nevejans,

Bernd Reck

и другие.

Progress in Polymer Science, Год журнала: 2021, Номер 114, С. 101362 - 101362

Опубликована: Янв. 18, 2021

Язык: Английский

Процитировано

240

Molecular Characterization of Polymer Networks DOI
Scott P. O. Danielsen, Haley K. Beech, Shu Wang

и другие.

Chemical Reviews, Год журнала: 2021, Номер 121(8), С. 5042 - 5092

Опубликована: Апрель 1, 2021

Polymer networks are complex systems consisting of molecular components. Whereas the properties individual components typically well understood by most chemists, translating that chemical insight into polymer themselves is limited statistical and poorly defined nature network structures. As a result, it challenging, if not currently impossible, to extrapolate from behavior full range performance entire network. therefore present an unrealized, important, interdisciplinary opportunity exert molecular-level, control on material macroscopic properties. A barrier sophisticated approaches techniques for characterizing structure often unfamiliar many scientists. Here, we critical overview current characterization available understand relation between resulting networks, in absence added fillers. We highlight methods characterize chemistry molecular-level strands junctions, gelation process which form network, dynamics mechanics final material. The purpose serve as detailed manual conducting these measurements but rather unify underlying principles, point out remaining challenges, provide concise chemists can plan strategies suit their research objectives. Because cannot be sufficiently characterized with single method, strategic combinations multiple required characterization.

Язык: Английский

Процитировано

239

Dynamic and reconfigurable materials from reversible network interactions DOI
Matthew J. Webber, Mark W. Tibbitt

Nature Reviews Materials, Год журнала: 2022, Номер 7(7), С. 541 - 556

Опубликована: Янв. 31, 2022

Язык: Английский

Процитировано

225

Biobased vitrimers: Towards sustainable and adaptable performing polymer materials DOI Creative Commons
Matteo Andrea Lucherelli, Antoine Duval, Luc Avérous

и другие.

Progress in Polymer Science, Год журнала: 2022, Номер 127, С. 101515 - 101515

Опубликована: Янв. 12, 2022

Язык: Английский

Процитировано

199

Elastic vitrimers: Beyond thermoplastic and thermoset elastomers DOI Creative Commons
Jiancheng Luo, Zoriana Demchuk, Xiao Zhao

и другие.

Matter, Год журнала: 2022, Номер 5(5), С. 1391 - 1422

Опубликована: Май 1, 2022

Язык: Английский

Процитировано

172