Anticancer activity of quantum size carbon dots: opportunities and challenges

Discover Nano, Год журнала: 2024, Номер 19(1)

Опубликована: Авг. 5, 2024

Abstract Research into the anticancer activity of quantum-sized carbon dots (CDs) has emerged as a promising avenue in cancer research. This CDs delves opportunities and challenges associated with harnessing potential these nanostructures for combating cancer. Quantum-sized dots, owing to their unique physicochemical properties, exhibit distinct advantages therapeutic agents. Opportunities lie tunable size, surface functionalization capabilities, biocompatibility, enabling targeted drug delivery imaging cells. However, we include challenges, comprehensive understanding underlying mechanisms, toxicity concerns, optimization synthesis methods enhanced efficacy. A succinct summary state research this area is given review, emphasizing exciting possibilities ongoing utilizing novel strategy treatment.

Язык: Английский

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Boron Nanocomposites for Boron Neutron Capture Therapy and in Biomedicine: Evolvement and Challenges

Biomaterials Research, Год журнала: 2025, Номер 29

Опубликована: Янв. 1, 2025

Cancer remains a major concern for human health worldwide. To fight the curse of cancer, boron neutron capture therapy is an incredibly advantageous modality in treatment cancer as compared to other radiotherapies. Due tortuous vasculature and around tumor regions, ( 10 B) compounds preferentially house into cells, creating large dose gradient between highly mingled cells normal cells. Epithermal or thermal bombardment leads tumor-cell-selective killing due generation heavy particles yielded from situ fission reaction. However, challenges nanocomposites’ development have been synthesis part well requirement selective targeting delivery therapeutic concentrations with nominal healthy tissue accumulation retention. circumvent above challenges, this review discusses boride nanocomposite design, safety, biocompatibility biomedical applications general public use. This sparks interest using nanocomposites agents repurposing them comorbidity treatments, future scientific opportunities, hope accelerate stimulus developing possible composite nanomedicine research

Язык: Английский

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Recent progress of nano-drugs in neutron capture therapy

Theranostics, Год журнала: 2024, Номер 14(8), С. 3193 - 3212

Опубликована: Янв. 1, 2024

As a developing radiation treatment for tumors, neutron capture therapy (NCT) has less side effects and higher efficacy than conventional therapy.Drugs with specific isotopes are indispensable counterparts of NCT, as they the indespensable part reaction.Since creation first second generations boron-containing reagents, NCT significantly advanced.Notwithstanding, extant medications, predominantly comprised small molecule boron medicines, have encountered challenges such monofunctionality, inadequate targeting hypermetabolism.There is an urgent need to promote research development new types drugs.Bio-nanomaterials can be introduced into realm nanotechnology give medications richer functionality significant adaptability.This complement advantages each other expected develop more drugs toxicity, low effects, better tumor targeting, high biocompatibility.In this review, we summarized progress nano-drugs in based on different sources used, attempts efforts made by relevant researchers combining nanomaterials hoping provide pivotal references promoting field radiotherapy.

Язык: Английский

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Three Dimension of Au-MnO2 Nanostructure as Agent of Synergistic Cancer Therapy: Chemo-/Photodynamic and Photothermal Approaches

Dalton Transactions, Год журнала: 2024, Номер 53(27), С. 11368 - 11379

Опубликована: Янв. 1, 2024

The design of multimodal cancer therapy was focused on reaching an efficient process and minimizing harmful effects patients.

Язык: Английский

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Targeted Drug Delivery with Photoluminescent Emitters: Applications in Diagnostic

Engineering materials, Год журнала: 2025, Номер unknown, С. 75 - 119

Опубликована: Янв. 1, 2025

Язык: Английский

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Dual co-doped fluorescent carbon dots for ultra-sensitive detection of Co2+ ions: Applications in food samples, bioimaging, and environmental monitoring

Inorganic Chemistry Communications, Год журнала: 2025, Номер unknown, С. 114716 - 114716

Опубликована: Май 1, 2025

Язык: Английский

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Recent Advances in Carbon Dots: Applications in Oral Diseases

ACS Applied Nano Materials, Год журнала: 2024, Номер unknown

Опубликована: Дек. 19, 2024

Over the years, oral and maxillofacial injuries, mainly caries, pulpitis, bone defects, cancer, often involve a variety of organs tissues, resulting in structural dysfunction, adverse effects on facial appearance, not only affecting people's chewing, swallowing other physiological functions, but also to physical mental health burden. As type carbon-based nanomaterial, carbon dots (CDs) have been widely used diagnosis treatment diseases due its excellent optical properties, good biocompatibility low toxicity. In addition, surface functionalization or passivation CDs can change properties CDs, such as water solubility chemiluminescence, broaden biomedical potential CDs. this review, latest research progress modified hard tissue regeneration, tumor treatment, antibacterial activity, dentin pulp complex teeth whitening, wound healing, drug release, fluorescence tracer bioimaging were reviewed. we discussed problems future direction development.

Язык: Английский

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Chemiluminescence of potassium permanganate and carbon dots and its analytical applications

Journal of Food Composition and Analysis, Год журнала: 2024, Номер unknown, С. 107156 - 107156

Опубликована: Дек. 1, 2024

Язык: Английский

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Comprehensive review of Carbon-based nanostructures: Properties, synthesis, characterization, and cross-disciplinary applications

Journal of Industrial and Engineering Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 1, 2024

Язык: Английский

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