Targeting Reactive Oxygen Species for Diagnosis of Various Diseases DOI Creative Commons

Moung Young Lee,

Dong‐Uk Lee, Dong‐Kug Choi

и другие.

Journal of Functional Biomaterials, Год журнала: 2024, Номер 15(12), С. 378 - 378

Опубликована: Дек. 15, 2024

Reactive oxygen species (ROS) are generated predominantly during cellular respiration and play a significant role in signaling within the cell between cells. However, excessive accumulation of ROS can lead to dysfunction, disease progression, apoptosis that organ dysfunction. To overcome short half-life relatively small amount produced, various imaging methods have been developed, using both endogenous exogenous means monitor settings. In this review, we discuss molecular mechanisms underlying production explore materials could be used detect overproduction, including iron-based materials, ROS-responsive chemical bond containing polymers, molecule biomaterials. We also techniques target overproduction. potentials established clinical methods, such as magnetic resonance (MRI), sonographic imaging, fluorescence imaging. other photoacoustic (PAI) Raman (RI) currently preclinical stage discussed. Finally, paper focuses on diseases associated with current future applications ROS-targeted While most widely condition is cardiovascular diseases, its potential extends into non-cardiovascular conditions, neurovascular, neurodegenerative, ROS-associated cancers, skin aging, acute kidney injury, inflammatory arthritis.

Язык: Английский

Assessment of Burn Severity Using Photoacoustic Imaging DOI Open Access
Yasuyuki Tsunoi

Nippon Laser Igakkaishi, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

熱傷は重症度により治療方針が異なるため,正確な診断が重要である.しかし,これまでに信頼性の高い診断法は確立されていない.光音響イメージング法は,皮膚全層を深さ分解的に画像化できるため,熱傷の診断に有用と考えられる.本稿では,光音響イメージング法の熱傷診断への応用について,近年の報告例を紹介するとともに,著者らの最近の研究としてLEDを光源に用いた受傷深度の診断法について解説する.

Язык: Английский

Процитировано

0
Targeting Reactive Oxygen Species for Diagnosis of Various Diseases DOI Creative Commons

Moung Young Lee,

Dong‐Uk Lee, Dong‐Kug Choi

и другие.

Journal of Functional Biomaterials, Год журнала: 2024, Номер 15(12), С. 378 - 378

Опубликована: Дек. 15, 2024

Reactive oxygen species (ROS) are generated predominantly during cellular respiration and play a significant role in signaling within the cell between cells. However, excessive accumulation of ROS can lead to dysfunction, disease progression, apoptosis that organ dysfunction. To overcome short half-life relatively small amount produced, various imaging methods have been developed, using both endogenous exogenous means monitor settings. In this review, we discuss molecular mechanisms underlying production explore materials could be used detect overproduction, including iron-based materials, ROS-responsive chemical bond containing polymers, molecule biomaterials. We also techniques target overproduction. potentials established clinical methods, such as magnetic resonance (MRI), sonographic imaging, fluorescence imaging. other photoacoustic (PAI) Raman (RI) currently preclinical stage discussed. Finally, paper focuses on diseases associated with current future applications ROS-targeted While most widely condition is cardiovascular diseases, its potential extends into non-cardiovascular conditions, neurovascular, neurodegenerative, ROS-associated cancers, skin aging, acute kidney injury, inflammatory arthritis.

Язык: Английский

Процитировано

1