Photoredox-Catalyzed C–H Functionalization Reactions

Chemical Reviews, Год журнала: 2021, Номер 122(2), С. 1925 - 2016

Опубликована: Сен. 29, 2021

The fields of C–H functionalization and photoredox catalysis have garnered enormous interest utility in the past several decades. Many different scientific disciplines relied on strategies including natural product synthesis, drug discovery, radiolabeling, bioconjugation, materials, fine chemical synthesis. In this Review, we highlight use reactions. We separate review into inorganic/organometallic catalysts organic-based catalytic systems. Further subdivision by reaction class─either sp2 or sp3 functionalization─lends perspective tactical for these methods synthetic applications.

Язык: Английский

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Organic thermally activated delayed fluorescence (TADF) compounds used in photocatalysis

Chemical Society Reviews, Год журнала: 2021, Номер 50(13), С. 7587 - 7680

Опубликована: Янв. 1, 2021

Organic compounds that show Thermally Activated Delayed Fluorescence (TADF) have become wildly popular as next generation emitters in organic light-emitting diodes (OLEDs), but since 2016, received significant and increasing attention photocatalysts.

Язык: Английский

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Site-Selective Direct C–H Pyridylation of Unactivated Alkanes by Triplet Excited Anthraquinone

Journal of the American Chemical Society, Год журнала: 2021, Номер 143(7), С. 3003 - 3012

Опубликована: Фев. 8, 2021

Site-selective C-H functionalization in chemical feedstocks is a challenging and useful reaction the broad field of research. Here, we report modular photochemical platform for site-selective pyridylation unactivated hydrocarbons via unique synergistic effects triplet excited anthraquinone an amidyl radical-based reverse hydrogen atom transfer (RHAT) agent. The selective tertiary secondary C(sp3)-H bonds abundant was achieved by employing various N-aminopyridinium salts highly fashion, thus providing new catalytic system direct construction high-value-added compounds under ambient conditions. Moreover, this operationally simple protocol applicable to variety linear-, branched-, cyclo-alkanes more complex molecules with high degrees site selectivity visible-light conditions, which provides rapid straightforward access versatile synthons upgrading mild, metal-free

Язык: Английский

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External photocatalyst-free C-H alkylation of N-sulfonyl ketimines with alkanes under visible light

Chinese Chemical Letters, Год журнала: 2023, Номер 34(9), С. 108509 - 108509

Опубликована: Апрель 28, 2023

Язык: Английский

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Organophotoelectrocatalytic C(sp²)–H alkylation of heteroarenes with unactivated C(sp³)–H compounds

Chemical Communications, Год журнала: 2024, Номер 60(42), С. 5502 - 5505

Опубликована: Янв. 1, 2024

An organophotoelectrocatalytic method for the C(sp 2 )–H alkylation of heteroarenes with unactivated 3 compounds via dehydrogenation cross-coupling was developed.

Язык: Английский

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Photo-triggered self-catalyzed fluoroalkylation/cyclization of unactivated alkenes: synthesis of quinazolinones containing the CF₂R group

Green Chemistry, Год журнала: 2020, Номер 23(1), С. 575 - 581

Опубликована: Дек. 10, 2020

A photo-triggered self-catalyzed fluoroalkylation/cyclization of quinazolinones containing unactivated alkenes with various fluoroalkyl bromides has been developed.

Язык: Английский

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Electrophotocatalytic C−H Functionalization of N‐Heteroarenes with Unactivated Alkanes under External Oxidant‐Free Conditions

ChemSusChem, Год журнала: 2021, Номер 15(6)

Опубликована: Дек. 30, 2021

The Minisci alkylation of N-heteroarenes with unactivated alkanes under external oxidant-free conditions provides an economically attractive route to access alkylated but remains underdeveloped. Herein, a new electrophotocatalytic strategy alkyl radicals from strong C(sp3 )-H bonds was reported for the following reactions in absence chemical oxidants. This realized first example cerium-catalyzed reaction directly abundant excellent atom economy. It is anticipated that general design principle would enrich catalytic strategies explore functionalizations H2 evolution.

Язык: Английский

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Aliphatic C–H Functionalization Using Pyridine N-Oxides as H-Atom Abstraction Agents

ACS Catalysis, Год журнала: 2022, Номер 12(16), С. 10499 - 10505

Опубликована: Авг. 10, 2022

The alkylation and heteroarylation of unactivated tertiary, secondary, primary C(sp3)-H bonds was achieved by employing an acridinium photoredox catalyst along with readily available pyridine Noxides as hydrogen atom transfer (HAT) precursors under visible light. Oxygen-centered radicals, generated single-electron oxidation the Noxides, are proposed key intermediates whose reactivity can be easily modified structural adjustments. A broad range aliphatic C-H substrates electron-donating or -withdrawing groups well various olefinic radical acceptors heteroarenes were tolerated.

Язык: Английский

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Visible-light-induced metal-free coupling of C(sp³)–H sources with heteroarenes

Green Chemistry, Год журнала: 2022, Номер 24(8), С. 3056 - 3080

Опубликована: Янв. 1, 2022

This critical review chronologically summarizes the metal-free coupling methodologies of C(sp 3 )–H sources with heteroarenes induced by visible light. The articles which are published up to January 2022 on this topic enclosed here.

Язык: Английский

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Radical-mediated photoredox hydroarylation with thiosulfonate

Chemical Communications, Год журнала: 2023, Номер 59(19), С. 2767 - 2770

Опубликована: Янв. 1, 2023

Radical-mediated photoredox hydroarylation reaction of unactivated alkenes using thiosulfonate compounds as key radical precursors to synthesize pyridyquinazolinone and pyrroloquinazolinone derivatives is described.

Язык: Английский

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