Abstract
Organolithium
compounds
are
among
the
most
versatile
and
widely
used
reagents
in
organic
synthesis.
However,
their
high
reactivity
basicity
have
historically
limited
use
as
direct
coupling
partners
metal-catalyzed
carbon—carbon
bond
forming
methods.
This
review
provides
an
update
to
advances
this
area,
with
a
focus
on
highlighting
reports
during
period
2011–2023,
that
revolutionized
field,
propelling
organolithium
forefront
of
strategies
for
constructing
new
C—C
bonds
using
transition-metal
catalysts.
Advanced Synthesis & Catalysis,
Год журнала:
2021,
Номер
363(23), С. 5235 - 5265
Опубликована: Ноя. 4, 2021
Abstract
Hydrazones,
as
universal
structural
units,
are
useful
synthons
for
the
formation
of
carbon–nitrogen
and
nitrogen−heteroatom
bonds.
Thus,
they
provide
new
methods
constructing
nitrogen‐containing
heterocycles.
In
recent
years,
especially
between
2017
2021,
many
efforts
have
been
made
to
exploit
hydrazone‐based
reactions
in
develop
more
powerful
effective
pathways
towards
synthesis
various
multifunctional
heterocyclic
compounds.
However,
despite
tremendous
amount
work
that
has
published
over
past
five
no
review
summarizes
significant
progress
preparation
nitrogen
heterocycles
via
intramolecular
cyclization
hydrazones
with
adjacent
unsaturated
bonds
or
intermolecular
systems.
Therefore,
this
strategies
used
synthesize
years.
It
discusses
corresponding
reaction
scopes,
limitations,
mechanisms,
problems.
magnified
image
Chemical Society Reviews,
Год журнала:
2023,
Номер
53(2), С. 883 - 971
Опубликована: Дек. 18, 2023
This
review
aims
to
collect
advancements
in
enantioselective
palladium-catalyzed
cyclization
reactions
over
the
past
eleven
years,
and
it
is
organized
into
thirteen
sections
depending
on
different
types
of
transformations
involved.
Organic Letters,
Год журнала:
2022,
Номер
24(19), С. 3440 - 3444
Опубликована: Май 11, 2022
An
efficient
Pd-catalyzed
asymmetric
allylic
substitution
cascade
of
4-hydroxy-2H-pyrones
with
meso-allyl
dicarbonates
has
been
developed
for
the
synthesis
kinetic
chiral
tetrahydro-1H-pyrano[4,3-b]benzofuran-1-one
products
in
≤87%
yield
and
≤99%
ee.
The
protocol
was
achieved
via
a
temperature-controlled
control
process,
which
illustrated
by
means
experimental
results
experiments.
reaction
could
be
conducted
on
gram
scale,
resulting
product
allows
several
transformations.
Organic Letters,
Год журнала:
2023,
Номер
25(32), С. 5963 - 5968
Опубликована: Авг. 4, 2023
A
palladium-catalyzed
asymmetric
annulative
dearomatization
of
phenols
with
butene
dicarbonate
is
reported,
enabling
twofold
decarboxylative
allylation
to
regioselectively
produce
a
range
spirocyclohexadienones
29-95%
yields
and
74-99%
ee.
catalytic
dearomative
formal
[4
+
2]
cyclization
1,1'-biphenyl-2,4'-diols
delivered
spiro[chromane-4,1'-cyclohexane]-2',5'-dien-4'-ones
high
enantioselectivity,
whereas
enantioenriched
spiro[cyclohexane-1,4'-quinoline]-2,5-dien-4-ones
were
generated
starting
from
2'-amino-[1,1'-biphenyl]-4-ols
as
1,4-dinucleophiles.
Chemical Communications,
Год журнала:
2023,
Номер
59(76), С. 11298 - 11319
Опубликована: Янв. 1, 2023
The
enantioselective
catalytic
cascade
involving
Tsuji-Trost
allylation
has
provided
a
viable
strategy
for
the
construction
of
multiple
asymmetric
C-C
and
C-X
centres
numerous
methods
have
been
developed
around
it
synthesis
various
vital
scaffolds.
synthetic
utility
this
was
enhanced
by
replacing
customary
allyl
acetates
with
ethylene
diacetates/dicarbonates,
vinyl
epoxides,
oxetanes,
carbonates,
cyclopropanes,
enynes,
dienes
using
transition-metal
catalysis.
One
more
milestone
achieved
when
metallaphotocatalysis
necessary
platform
these
cascades
cheaper
metal.
This
review
will
provide
summary
from
2015.
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(5), С. 3177 - 3183
Опубликована: Фев. 8, 2022
A
direct
1,2-dibromination
method
of
alkenes
is
realized
using
1,3-dibromo-5,5-dimethylhydantoin
(DBDMH)
as
a
bromine
source.
This
reaction
proceeds
under
mild
conditions
without
the
use
catalyst
and
an
external
oxidant.
Various
sorts
alkene
substrates
are
transformed
into
corresponding
1,2-dibrominated
products
in
good
to
excellent
yields
with
broad
substrate
scope
exclusive
diastereoselectivity.
offers
green
practical
approach
synthesize
vicinal
dibromide
compounds.
