Angewandte Chemie,
Год журнала:
2022,
Номер
134(48)
Опубликована: Окт. 7, 2022
Abstract
The
carbon
dioxide
(CO
2
)
capture
and
utilization
has
attracted
a
great
attention
in
organic
synthesis.
Herein,
an
unpresented
transient
stabilization
effect
(TSE)
of
CO
is
disclosed
well
applied
to
the
electrochemical
hydrogenation
azo
compounds
hydrazine
derivatives.
Mechanistic
experiments
computational
studies
imply
that
can
radical
anion
intermediates
protect
from
potential
degradation
reactions,
finally
released
through
decarboxylation.
promotion
was
further
demonstrated
work
preliminary
study
reductive
coupling
α‐ketoesters
vicinal
diol
For
reactions
mentioned
above,
indispensable.
presented
results
shed
light
on
different
usage
could
inspire
novel
experimental
design
by
using
as
protecting
group.
Organic & Biomolecular Chemistry,
Год журнала:
2022,
Номер
20(46), С. 9127 - 9131
Опубликована: Янв. 1, 2022
An
Fe-catalyzed
unprotected
hydroxylamine
mediated
Heck-type
coupling
between
sulfinic
acids
and
alkenes
furnished
structurally
important
(
E
)-vinyl
sulfones
with
moderate
to
good
yields,
high
atom-economy
regioselectivity.
Organic Letters,
Год журнала:
2024,
Номер
26(18), С. 4018 - 4023
Опубликована: Апрель 26, 2024
Although
extraordinary
advances
have
been
achieved
by
the
transition-metal
catalysis
system,
there
is
an
urgent
need
to
explore
and
develop
alternative
methodologies
that
are
more
environmentally
friendly.
Herein,
we
report
electrochemical
chlorosulfonylation
of
alkenes
using
a
wide
range
sulfonyl
chlorides
with
inexpensive,
degradable,
commercially
available
organoboron
as
promoter.
Furthermore,
this
protocol
employs
convergent
paired
electrolysis,
reducing
for
sacrificial
anodes
minimizing
extent
hydrogen
evolution.
Organic Letters,
Год журнала:
2023,
Номер
25(31), С. 5911 - 5915
Опубликована: Авг. 2, 2023
An
unprecedented
Csp3-H
imination
reaction
using
arylazo
sulfones
as
the
readily
accessible
and
stable
N
source
is
reported.
The
synthetic
virtues
are
demonstrated
through
mild
conditions,
simple
operation,
good
air
compatibility,
functional
group
tolerance,
well
suitability
for
gram-scale
reaction.
resulting
imines
can
be
further
converted
to
α-amino
acids.
presented
results
shed
light
on
an
unusual
usage
of
will
inspire
novel
experimental
design
by
source.
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(9), С. 6418 - 6425
Опубликована: Апрель 25, 2022
A
method
for
the
rapid
synthesis
of
polycyclic
3,3'-biindole
derivatives
has
been
developed
through
AgOTf-catalyzed
nucleophilic
addition
and
cycloisomerization
processes.
The
cascade
reaction
employs
readily
accessible
indoles
their
N-2-formylphenyl
provides
functionalized
3,3'-biindoles
in
moderate
to
good
yields
under
mild
conditions.
This
is
highly
efficient
takes
only
several
minutes
(∼5
min).
Notably,
also
highlighted
by
a
Selectfluor-mediated
oxidation
that
quickly
generates
oxindole
derivatives.
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(16), С. 11131 - 11140
Опубликована: Авг. 4, 2022
We
report
an
electrochemical
intramolecular
[3
+
2]
cyclization
of
alkynyl
enaminones
in
a
user-friendly
undivided
cell
under
constant
current
conditions
without
oxidant
and
catalyst,
indeno[1,2-c]pyrrole
derivatives
could
be
obtained
good
to
excellent
yields.
Notably,
preliminary
substituent-controlled
selective
transformation
is
also
achieved
electrocatalysis
alone,
(R4
≠
H)
or
indanone
=
prepared
directly
adding
base
heating
process.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
11(9), С. 2528 - 2533
Опубликована: Янв. 1, 2024
A
novel
strategy
for
the
selective
synthesis
of
(
E
)-vinyl
sulfone
derivatives
from
p
-tosylmethyl
isocyanide
(TosMIC)
and
ortho
-substituted
benzaldehydes
has
been
established.
Synthesis,
Год журнала:
2022,
Номер
54(23), С. 5245 - 5252
Опубликована: Июль 13, 2022
Abstract
A
facile
method
to
synthesize
azo
compounds
from
hydrazine
derivatives
is
developed.
This
represents
the
unprecedented
example
of
Selectfluor-mediated
oxidative
dehydrogenation
derivatives.
The
reaction
might
proceed
through
N-fluorination
and
elimination
processes.
protocol
exhibits
key
features
including
simple
operation,
mild
conditions,
good
functional
group
tolerance,
high
efficiency.
Moreover,
advantage
also
highlighted
by
conversion
a
sulfonyl-substituted
compound
furnish
acetanilide
in
excellent
yield
under
4
W
blue
LED
irradiation.
Angewandte Chemie,
Год журнала:
2022,
Номер
134(48)
Опубликована: Окт. 7, 2022
Abstract
The
carbon
dioxide
(CO
2
)
capture
and
utilization
has
attracted
a
great
attention
in
organic
synthesis.
Herein,
an
unpresented
transient
stabilization
effect
(TSE)
of
CO
is
disclosed
well
applied
to
the
electrochemical
hydrogenation
azo
compounds
hydrazine
derivatives.
Mechanistic
experiments
computational
studies
imply
that
can
radical
anion
intermediates
protect
from
potential
degradation
reactions,
finally
released
through
decarboxylation.
promotion
was
further
demonstrated
work
preliminary
study
reductive
coupling
α‐ketoesters
vicinal
diol
For
reactions
mentioned
above,
indispensable.
presented
results
shed
light
on
different
usage
could
inspire
novel
experimental
design
by
using
as
protecting
group.
