Electrochemical Dearomatization of Indoles: Access to Diversified Functionalized Spirocyclic Indolines DOI
Jian Wang,

Ranran Zhu,

Yufen Zhao

и другие.

Topics in heterocyclic chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

Electrochemical Oxidation of Indoles to Access Tryptanthrins at Room Temperature DOI

Ziyi Guo,

Yi Liu, Hang Li

и другие.

Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 366(2), С. 225 - 231

Опубликована: Ноя. 21, 2023

Abstract An electrooxidative reconstruction of the indole core under ambient conditions is reported, resulting in construction tryptanthrins. This electrochemical strategy simplifies molecular skeleton‐hopping by employing commercially available NH‐indole feedstock as starting materials. Furthermore, synthetic value this skeletal was demonstrated divergent further transformations. A preliminary mechanistic investigation involving control experiments and cyclovoltammetric studies showed indispensability electricity, well importance oxygen TEMPO, thereby revealing a possible reaction pathway.

Язык: Английский

Процитировано

2
A SmI2-mediated reductive cyclisation reaction using the trifluoroacetamide group as the radical precursor DOI Creative Commons
Kōta Yoshioka, Hiroki Iwasaki,

Mako Hanaki

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(10), С. 1988 - 1992

Опубликована: Янв. 1, 2024

A SmI 2 -mediated reductive cyclisation using trifluoroacetamide groups as radical precursors and alkynes acceptors, which is the first example of an acyclic amide group in a cyclisation, afforded 2-trifluoromethylindolines.

Язык: Английский

Процитировано

0
Synthesis of Fluorinated Spiroindolenines by Transition Metal‐Catalyzed Indole Dearomatizations DOI Creative Commons
Floris Buttard,

Meriem Daghmoum,

Mathieu Arribat

и другие.

Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(20), С. 4244 - 4252

Опубликована: Май 25, 2024

Abstract A strategy to access fluorinated spiroindolenines has been developed, involving a selective functionalization of indoles with moieties and subsequent catalytic dearomatization. Trifluomethylthio (SCF 3 ), diethyl phosphono(difluoromethyl)thio 2 P(O)(OEt) ) (phenylsulfonyl)difluoromethyl (CF SO Ph) groups were embedded at the C2 position indole derivatives substituted alkynes, allenes, allyl carbonate C3 position. gold‐catalyzed cycloisomerization gave five spiroindolenines, an enantioselective palladium catalyzed cyclization provided 10 spirocyclic products up 77% ee.

Язык: Английский

Процитировано

0
Modern electrosynthesis of spiro compounds DOI
Michaïl N. Elinson,

Yu. E. Ryzhkova,

Fedor V. Ryzhkov

и другие.

Russian Chemical Bulletin, Год журнала: 2024, Номер 73(7), С. 1845 - 1865

Опубликована: Июль 1, 2024

Язык: Английский

Процитировано

0
Electrochemical Dearomatization of Indoles: Access to Diversified Functionalized Spirocyclic Indolines DOI
Jian Wang,

Ranran Zhu,

Yufen Zhao

и другие.

Topics in heterocyclic chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0