
Research Square (Research Square), Год журнала: 2023, Номер unknown
Опубликована: Окт. 30, 2023
Язык: Английский
Research Square (Research Square), Год журнала: 2023, Номер unknown
Опубликована: Окт. 30, 2023
Язык: Английский
Nature Chemistry, Год журнала: 2024, Номер 17(1), С. 101 - 110
Опубликована: Окт. 11, 2024
Язык: Английский
Процитировано
3Synthesis, Год журнала: 2024, Номер unknown
Опубликована: Сен. 19, 2024
Abstract N-Heterocyclic nitreniums (NHNs) are isoelectronic and isostructural analogues of N-heterocyclic carbenes (NHCs). Unlike NHCs, NHNs much less developed. While a comprehensive understanding NHN reactivity remains elusive, recent advancements have demonstrated their utility as Lewis acid catalysts, photoreductants, photooxidants, leading to several reaction patterns. In this short review, we focus on the applications in photoredox reactions. We also discuss mechanisms behind these transformations outline future research directions. 1 Introduction 2 Application Nitreniums Photoreductants 3 Facilitate Photohomolysis 4 Photooxidants 5 Conclusion
Язык: Английский
Процитировано
3Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
An efficient photoactive charge transfer complex protocol for the synthesis of phenanthridine derivatives by reaction 2-isocyanobiaryls with α-chloro esters is established.
Язык: Английский
Процитировано
0The Journal of Physical Chemistry A, Год журнала: 2025, Номер unknown
Опубликована: Май 17, 2025
Cyclic nitrenium ions (CNIs) are generally stable and have found applications in chemistry, including biochemistry. five-membered 1,2,3-triazolium (CFTIs) a special class of CNIs; such moieties few medicinally important species. Though they isoelectronic to N-heterocyclic carbenes (NHCs), exhibit electrophilic properties (unlike nucleophilic NHCs). A quantum chemical studies were reported, but extensive study on CFTIs is required understand their electronic features design species with tailored properties. In this work, thorough analysis has been carried out the standard CFTI (1,3-dimethyl-1,2,3-triazolium ion). Hydride ion affinity fluoride parameters estimated evaluate Lewis acidic character CFTIs. Also, electrophilicity these terms global index (ω) values. The complexation energies PMe3 (ΔHPMe3) 1,3-dimethylimidazol-2-ylidene (ΔHNHC) also estimated. modulation as function substitution ring fusion evaluated. correlation between ΔHPMe3 ΔHNHC very high (R = 0.99); helps identifying that may character.
Язык: Английский
Процитировано
0ChemistryEurope, Год журнала: 2025, Номер unknown
Опубликована: Июнь 1, 2025
Considering the appealing synthetic properties of oxygenous feedstocks and organoboron compounds, direct deoxygenative borylation is a very desirable chemical transformation. Directly converting acyl chlorides into alkylboronates through an unknown but valuable reaction. Herein, relatively straightforward one‐step methodology reported where N‐heterocyclic nitrenium (NHN) ion acts as photocatalyst under visible light to produce benzylboronates directly from aroyl in absence metals or additives. A large variety are well tolerated reaction conditions. Mechanistic investigations density functional theory calculations support that NHN species involved radical formation DMAc‐H 2 O/B cat contributes alkylboronates.
Язык: Английский
Процитировано
0Asian Journal of Organic Chemistry, Год журнала: 2023, Номер 12(6)
Опубликована: Апрель 22, 2023
Abstract Herein, we developed a fluoride‐mediated nucleophilic aromatic amination of chloro‐1 H ‐1,2,3‐triazolium salts. Various functional groups were tolerated in this reaction, which enabled the synthesis functionalized amino‐1 In addition, investigated catalytic properties triazolium‐based N‐heterocyclic imines (NHIs) for cyanosilylation ketones. The substituent was found to play crucial role inducing high activity.
Язык: Английский
Процитировано
7Organic Chemistry Frontiers, Год журнала: 2023, Номер 11(3), С. 673 - 683
Опубликована: Ноя. 28, 2023
We report an efficient and versatile catalytic N-heterocyclic nitrenium charge transfer complex strategy for the single-electron reduction of chloroform, resulting in generation dichloromethyl radical use various transformations.
Язык: Английский
Процитировано
7Chemical Science, Год журнала: 2023, Номер 14(43), С. 12034 - 12040
Опубликована: Янв. 1, 2023
Bench-stable N-heterocyclic nitrenium ions were used for the efficient electrophilic amination of organometallic nucleophiles. The previously unexplored N -alkyl/aryl triazane intermediates reduced to produce a diverse scope primary amines.
Язык: Английский
Процитировано
4Chinese Chemical Letters, Год журнала: 2024, Номер unknown, С. 110383 - 110383
Опубликована: Авг. 1, 2024
Язык: Английский
Процитировано
1Journal of Computational Chemistry, Год журнала: 2024, Номер unknown
Опубликована: Окт. 30, 2024
Abstract Cyclic nitrenium ions containing five‐membered and six‐membered rings are available, however, the seven‐membered cyclic (azepinium ions) rare. The chemistry of these species is related to their stability originating from aromaticity due 6π electrons. Very few theoretical experimental studies have been conducted on azepinium ions. Related clozapine olanzapine cations (diazepinium were observed during drug metabolism studies. In this work, quantum chemical analysis has carried out estimate stability, aromaticity, electrophilicity several derivatives A designed carry Δ E S‐T values in range 50 kcal/mol favoring singlet state; π donating groups at 2nd position increase singlet‐triplet energy differences. Most substituents reduce NICS(1) compared parent system. Ring fusion with heterocyclic generally increases ion ring systems. parameters estimated terms HIA, FIA, ω indicate that it possible fine‐tune properties appropriate modulation.
Язык: Английский
Процитировано
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