Progress in heterocyclic chemistry, Год журнала: 2023, Номер unknown, С. 251 - 280
Опубликована: Янв. 1, 2023
Язык: Английский
Organic Letters, Год журнала: 2023, Номер 25(40), С. 7298 - 7303
Опубликована: Окт. 3, 2023
An unprecedented protocol for a Rh(III)-catalyzed [3 + 2] annulation from simple and readily available enaminones iodonium ylides has been developed. The novel strategy allows access to new class of structurally diverse tetrahydro-indolones with high efficiency broad substrate scope. In addition, this transformation represents the first example selective alkenyl C–H bond functionalization enaminones. Finally, potential applications are demonstrated through gram-scale reaction late-stage modification.
Язык: Английский
Процитировано
38
ACS Omega, Год журнала: 2024, Номер 9(19), С. 20728 - 20752
Опубликована: Май 6, 2024
Benzofurans have intrigued both pharmaceutical researchers and chemists owing to the medicinal usage of their derivatives against copious disease-causing agents (i.e., bacteria, viruses, tumors). These heterocyclic scaffolds are pervasively encountered in a number natural products drugs. The ever-increasing utilization benzofuran as persuaded devise novel facile methodological approaches assemble biologically potent nucleus. This review summarizes current developments regarding innovative synthetic routes catalytic strategies procure synthesis heterocycles with corresponding mechanistic details, reported by several research groups during 2021-2023.
Язык: Английский
Процитировано
11
Angewandte Chemie International Edition, Год журнала: 2023, Номер 62(23)
Опубликована: Апрель 6, 2023
Investigations into C-H amidation reactions catalysed by cationic half-sandwich d6 metal complexes revealed that the indenyl-derived catalyst [Ind*RhCl2 ]2 significantly accelerated directed ortho of benzoyl silanes using 1,4,2-dioxazol-5-ones. Ring slippage involving a haptotropic η5 to η3 rearrangement indenyl complex proposedly enables ligand substitution at centre proceed via associative, rather than dissociative pathways, leading significant rate and yield enhancements. Intriguingly, this phenomenon appears specific for weakly coordinating carbonyl-based directing groups with no acceleration observed corresponding strongly nitrogen-based groups.
Язык: Английский
Процитировано
17
Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(22), С. 5717 - 5734
Опубликована: Янв. 1, 2023
Vinylene carbonate (VC) has emerged as a promising coupling partner to participate in various attractive C–H conversions and implement an increasing number of novel reactions. In this review, we provide summary the advancements achieved metal-catalyzed functionalization using VC.
Язык: Английский
Процитировано
16
Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(9), С. 1457 - 1464
Опубликована: Апрель 14, 2023
Abstract In this study, Rh(III)‐catalyzed C−H bifunctionalization and direct vinylene annulation of sulfoxonium ylides N ‐carbamoylindoles with carbonate was accomplished, which afforded a series naphthalenones containing β‐ketosulfoxonium ylide moiety, isocoumarins, pyrimidones. This protocol featured mild conditions, broad substrate scope, functional‐groups compatibility. addition, related applications preliminary mechanistic exploratory were also investigated magnified image
Язык: Английский
Процитировано
14
Organic Letters, Год журнала: 2023, Номер 25(18), С. 3206 - 3209
Опубликована: Май 4, 2023
Isoquinoline is a privileged structure in many bioactive compounds and valuable ligands. Transition-metal-catalyzed oxidative annulation of imine derivatives has become promising synthetic method; however, catalytic synthesis 3,4-nonsubstituted isoquinolines by formal acetylene been scarce to date. Herein, we introduce vinyl selenone as an effective surrogate for the Rh-catalyzed annulative coupling under mild conditions. The Se fragment can be recovered diselenide recycled. product readily converted 1-aminoisoquinolines.
Язык: Английский
Процитировано
11
Green Chemistry, Год журнала: 2023, Номер 25(11), С. 4282 - 4291
Опубликована: Янв. 1, 2023
The chemical upcycling of poly(bisphenol A carbonate) was carried out through organocatalysis using α-hydroxyketones as nucleophiles, leading to valuable vinylene carbonates.
Язык: Английский
Процитировано
11
Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(20), С. 3400 - 3412
Опубликована: Сен. 6, 2023
Abstract Recently, vinylene carbonate has been developed as a powerful synthon in transition metal‐catalyzed C−H bond activation/cyclization reactions. This review introduces recent progress the use of reactant, by analyzing and comparing reaction models involving surrogate ethynol, acetylene, acetylation reagents or other reactants, while addressing related mechanisms synthetic applications.
Язык: Английский
Процитировано
11
Tetrahedron, Год журнала: 2024, Номер 154, С. 133854 - 133854
Опубликована: Фев. 2, 2024
Язык: Английский
Процитировано
4
Chemical Communications, Год журнала: 2024, Номер 60(26), С. 3571 - 3574
Опубликована: Янв. 1, 2024
Herein, a novel Pd-catalyzed denitrogenation/vinylation of benzotriazinones using vinylene carbonate as the vinylation reagent is reported. This transformation demonstrates an unprecedented skeletal editing approach, effectively converting NN to CC fragments
Язык: Английский
Процитировано
4