Post-functionalization of Click-Derived 1,2,3-Triazoles

Materials horizons, Год журнала: 2024, Номер unknown, С. 637 - 670

Опубликована: Янв. 1, 2024

Язык: Английский

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Multicomponent cyclization with azides to synthesize N-heterocycles

Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(40), С. 8054 - 8074

Опубликована: Янв. 1, 2023

The review focus on multicomponent reactions of azides for the construction N-heterocycles in recent 10 years.

Язык: Английский

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Copper(I)‐Catalyzed Interrupted Click Reaction: Synthesis of 1,4,5‐Trisubstituted 5‐Chloro‐1,2,3‐Triazoles

European Journal of Organic Chemistry, Год журнала: 2023, Номер 26(42)

Опубликована: Авг. 25, 2023

Abstract 5‐Halo‐1,2,3‐triazoles are important scaffolds in organic chemistry, but current click reactions cannot produce 1,4,5‐trisubstituted 5‐chloro‐1,2,3‐triazoles a simple way. Herein, we disclosed Cu(I)‐catalyzed interrupted reaction, using N ‐chlorophthalimide as an electrophilic chlorine source, enabling the facile synthesis of one step from readily available terminal alkynes and azides. Complete control regioselectivities with broad substrate scope was accomplished by this approach. Furthermore, novel epoxidation developed 5‐chloro‐triazole substrate, which could be further applied various transformations.

Язык: Английский

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Five-membered ring systems: with more than one N atom

Progress in heterocyclic chemistry, Год журнала: 2023, Номер unknown, С. 281 - 332

Опубликована: Янв. 1, 2023

Язык: Английский

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