Abstract
Sulfonium
salts
are
typically
bench‐stable
and
readily
available
reagents
that
showcase
diverse
chemical
reactivities.
Owing
to
these
synthetically
valuable
features,
sulfonium
salt
chemistry
has
witnessed
considerable
momentum
over
the
past
decades.
Particularly,
merger
of
electrosynthesis
enabled
utilization
electric
current
in
place
cost‐intensive
hazardous
redox
agents
maximize
attractive
characteristics
salts.
Additionally,
electrochemistry
allowed
chemists
dial
desired
potential,
offering
selective
access
target
products
otherwise
unattainable
by
either
thermal
or
photochemical
manifolds.
These
advantages
led
major
advances
chemistry.
Thus,
we,
herein,
provide
an
overview
early
pioneering
findings
recent
progress
devoted
organic
associated
with
until
December
2024,
aiming
stimulate
future
this
rapidly
evolving
arena.
Organic Letters,
Год журнала:
2023,
Номер
25(15), С. 2606 - 2610
Опубликована: Апрель 11, 2023
The
mild
and
efficient
palladium-catalyzed
pyrrolidin-2-yl
tetrahydrofuran-2-yl
methylation
of
(hetero)arenes
has
been
developed.
A
wide
range
underwent
the
regioselective
thianthrenation
to
generate
arylthianthrenium
triflate,
developed
Pd-catalyzed
alkene
carboamination
carboalkoxylation
reactions
afforded
corresponding
biologically
important
pyrrolidine
tetrahydrofuran
derivatives.
Mechanistic
studies
indicated
that
this
reaction
proceeds
through
a
syn-heteropalladation
mechanistic
pathway.
demonstrated
late-stage
functionalization
enantioselective
will
help
promote
potential
application
established
method
in
organic
synthesis
related
fields.
Synthesis,
Год журнала:
2023,
Номер
55(18), С. 2833 - 2842
Опубликована: Янв. 26, 2023
Abstract
Selective
functionalization
via
cleavage
of
the
C–N
bond
amines
has
proven
to
be
challenging
partly
because
its
relatively
high
dissociation
energy,
even
though
are
abundant
and
readily
available.
To
meet
this
challenge,
many
new
transformations
based
on
pre-activation
before
have
been
developed.
Among
them,
conversion
into
quaternary
ammonium
salts
certain
advantages,
such
as
easy
preparation
from
primary,
secondary,
or
tertiary
amines,
well
stable
storage
usage.
Although
transition
metal
catalysis
frequently
applied
for
developing
oxidative
addition
salts,
recent
studies
shown
a
dimension
by
using
green
electro-
photochemical
tools.
In
short
review,
advances
in
electro-,
photo-,
photoelectrochemical
driven
synthetic
applications
summarized
discussed.
1
Introduction
2
Electrochemical
Driven
Transformations
3
Photochemical
4
Photoelectrochemical
5
Conclusion
Outlook
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
21(18), С. 3789 - 3793
Опубликована: Янв. 1, 2023
We
developed
an
efficient
palladium-catalyzed
fluorosulfonylation
reaction
of
aryl
thianthrenium
salts
to
smoothly
prepare
various
sulfonyl
fluorides
using
cheap
Na2S2O4
as
a
convenient
source
in
combination
with
N-fluorobenzenesulfonimide
(NFSI)
ideal
fluorine
under
mild
reduction
conditions.
A
one-pot
synthesis
starting
from
arenes
was
established
well
without
the
need
for
separating
salts.
The
practicality
this
protocol
demonstrated
by
gram-scale
synthesis,
derivatization
reactions,
and
excellent
yields.
Abstract
Sulfonium
salts
are
typically
bench‐stable
and
readily
available
reagents
that
showcase
diverse
chemical
reactivities.
Owing
to
these
synthetically
valuable
features,
sulfonium
salt
chemistry
has
witnessed
considerable
momentum
over
the
past
decades.
Particularly,
merger
of
electrosynthesis
enabled
utilization
electric
current
in
place
cost‐intensive
hazardous
redox
agents
maximize
attractive
characteristics
salts.
Additionally,
electrochemistry
allowed
chemists
dial
desired
potential,
offering
selective
access
target
products
otherwise
unattainable
by
either
thermal
or
photochemical
manifolds.
These
advantages
led
major
advances
chemistry.
Thus,
we,
herein,
provide
an
overview
early
pioneering
findings
recent
progress
devoted
organic
associated
with
until
December
2024,
aiming
stimulate
future
this
rapidly
evolving
arena.
