Royal Society of Chemistry eBooks, Год журнала: 2024, Номер unknown, С. 1 - 31
Опубликована: Дек. 18, 2024
In the introduction chapter we introduce volume and its three sections, namely critical reviews, highlights on recent “hot” topics SPR lectures in photochemistry. Furthermore, includes most significant editorial releases photochemistry 2023, by presenting awards, handbooks, special issues reviews.
Язык: Английский
Chemical Reviews, Год журнала: 2024, Номер 124(11), С. 7214 - 7261
Опубликована: Май 16, 2024
In recent years, visible light-induced reactions of diazo compounds have attracted increasing attention in organic synthesis, leading to improvement existing reactions, as well the discovery unprecedented transformations. Thus, photochemical or photocatalytic generation both carbenes and radicals provide milder tools toward these key intermediates for many valuable However, vast majority transformations represent new reactivity modes compounds, which are achieved by decomposition photoredox catalysis. particular, use a redox-active photocatalysts opens avenue plethora radical reactions. The application methods led inaccessible classical associated with metal carbenes. most cases, act sources but can also serve acceptors. Importantly, described processes operate under mild, practical conditions. This Review describes this subfield compound chemistry, particularly focusing on advancements.
Язык: Английский
Процитировано
59
Chemical Communications, Год журнала: 2023, Номер 59(48), С. 7346 - 7360
Опубликована: Янв. 1, 2023
This article discusses the photochemistry of several diazo compounds undergoing visible light-mediated photolysis to generate free carbenes (or other highly reactive intermediates), which can be sequentially trapped by different reacting partners.
Язык: Английский
Процитировано
46
Chemical Communications, Год журнала: 2024, Номер 60(16), С. 2125 - 2136
Опубликована: Янв. 1, 2024
In this feature article, we focus on the photochemical strategy for construction of heterocyclic skeletons, specifically highlighting methods that employ visible light-promoted carbene transfer reactions.
Язык: Английский
Процитировано
22
Organic Letters, Год журнала: 2025, Номер 27(2), С. 709 - 714
Опубликована: Янв. 7, 2025
Herein, we present a visible-light-induced protocol for the synthesis of highly functionalized oxo-bridged oxocine skeletons. This method generates carbenes via ortho-acyl diazo compounds, which are rapidly intercepted by oxygen atom an intermolecular acyl group to form cyclic 1,3-dipole. The in situ generated reactive 1,3-dipole undergoes facile formal [4 + 3] cycloaddition with alkenyl pyrazolinone, yielding [4.2.1]-oxo-bridged compounds.
Язык: Английский
Процитировано
2
Chemical Society Reviews, Год журнала: 2024, Номер 53(10), С. 4926 - 4975
Опубликована: Янв. 1, 2024
In search for the perfect wave(length). This review is dedicated to recent efforts in development of visible light driven photochemical strategies occurring coloured organic compounds.
Язык: Английский
Процитировано
12
Chemical Science, Год журнала: 2023, Номер 14(24), С. 6663 - 6668
Опубликована: Янв. 1, 2023
A highly atom- and step-economy diastereoselective copper-mediated direct intramolecular cyclopropanation method to synthesize cyclopropane-fused γ-lactones lactams from distal olefinic acetate was disclosed.
Язык: Английский
Процитировано
11
Journal of the American Chemical Society, Год журнала: 2025, Номер unknown
Опубликована: Апрель 10, 2025
Herein, we disclose the discovery and development of a site-, regio-, diastereo-, enantioselective aryl C-H bond cyclopropylation using diazomethyl hypervalent iodine reagents, styrenes, paddlewheel dirhodium carboxylate catalysts. A key aspect this work was catalytic generation chiral Rh(II) carbene through an electrophilic aromatic substitution with carbynoids. The strategy allows construction cyclopropane rings bonds from feedstocks drug molecules promises to reach unexplored "cyclopropanated" chemical space highly difficult by current strategies.
Язык: Английский
Процитировано
0
Nature Communications, Год журнала: 2025, Номер 16(1)
Опубликована: Апрель 21, 2025
Conventional methods for thioglycoside activation often rely on precious and toxic platinum group metals. Here, we report a catalytic glycosylation strategy employing diazo-thioglycoside donors activated by earth-abundant iron or photosensitizer-free blue light conditions. It confers orthogonal reactivity relative to most glycosyl donors, including widely used thioglycosides alkyne-based thereby enabling one-pot synthesis of glycans. The Thorpe-Ingold-like effect drives the proximity iron- blue-light-generated carbenes sulfur atom thioglycosides. This approach accommodates diverse protecting groups nucleophiles. applies various derived from glucose, mannose, galactose, rhamnose, xylose, lactose, 2-deoxyamino furanose derivatives such as ribose arabinose. Moreover, demonstrate robustness this methodology through challenging 1,2-cis furanosides, late-stage modifications biomolecules like cholesterol, drug simvastatin gram scale, along with iterative hexasaccharides.
Язык: Английский
Процитировано
0
Organic Letters, Год журнала: 2024, Номер 26(28), С. 6035 - 6040
Опубликована: Июль 10, 2024
Fused-cyclopropane ring-containing γ-lactone compounds are versatile building blocks in many fields, including the synthesis of biologically active compounds. Here, we report light-driven intramolecular cyclopropanation alkene-tethered
Язык: Английский
Процитировано
2
Organic Letters, Год журнала: 2024, Номер 26(27), С. 5752 - 5757
Опубликована: Июль 1, 2024
A new self-cyclopropanation of 1,3-diphenylpropane-1,3-dione, leading to tetrasubstituted cyclopropane containing three contiguous stereogenic centers with high stereoselectivity, has been achieved through violet-light-emitting diode-irradiated photocatalysis, featuring both cycloaddition and a distinctive rearrangement. Diverging from conventional cyclopropanation pathways, this reaction yields unprecedented rearrangement cascade reactions.
Язык: Английский
Процитировано
1