Triazenolysis of Alkenes: Aza-version of Ozonolysis DOI Creative Commons
Mark Gandelman, Alexander N. Koronatov, Pavel А. Sakharov

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Окт. 30, 2023

Abstract Numerous applications of alkenes exist due to their abundance and versatility in chemical transformations. In this study, we present a unique novel transformation alkenes, the aza-version canonical ozonolysis reaction, which termed as triazenolysis. This process offers non-trivial previously unfeasible synthetic disconnection, allowing cleavage C=C double bond into two new C-N bonds reductive manner. We carefully examined applicability finding that diverse cyclic are suitable for developed process. Furthermore, an example acyclic alkene, illustrating potential expanding triazenolysis other counterparts. Through DFT calculations, explored mechanism key step demonstrated significance Lewis acid catalysis achieving desired transformation.

Язык: Английский

Multimodal Molecular Motion in the Rotaxanes and Catenanes Incorporating Flexible Calix[n]phyrin Stations DOI Creative Commons
Rafał A. Grzelczak, Tymoteusz Basak, Bartosz Trzaskowski

и другие.

Angewandte Chemie, Год журнала: 2024, Номер 137(1)

Опубликована: Авг. 27, 2024

Abstract The synthesis of [2]rotaxanes stoppered with one or two dipyrromethane groups has opened a route for the construction mechanically interlocked molecules incorporating various porphyrinoid stations. exploitation those precursors allowed creation [3]rotaxanes and [2]catenanes based on calix[4]phyrin motif, presenting intriguing molecular dynamics. intrinsic flexibility introduction new type motion within rotaxanes, termed fluttering. latter involved bending axle, interconverting angular‐shaped stereoisomers rotaxane through planarised transition state. Simple chemical transformations, i.e. methylation (de)protonation [3]rotaxane [2]catenane controllable transformations conformationally flexible calix[4]phyrin‐incorporated porphyrinoids.

Язык: Английский

Процитировано

0
1.1 Sulfonyl Fluorides and Acyl Fluorides DOI
Joey Lai, Brodie J. Thomson, Glenn M. Sammis

и другие.

Опубликована: Янв. 1, 2024

Abstract Sulfonyl fluorides have numerous applications in both synthetic organic chemistry as fluorinating agents and precursors to sulfur(VI) moieties, chemical biology covalent inhibitors probes. The utility of sulfonyl arises from the properties S—F bond, high bond strength polarization imparts stability chemoselectivity that differentiates this group other halides. Likewise, acyl found widespread use synthesis reactive intermediates. increased toward hydrolysis aminolysis comparison chlorides bromides are a result relative electrostatic C—F bond. In review, we provide an overview approaches these valuable motifs, with focus on versatile easy-to-handle protocols.

Язык: Английский

Процитировано

0
Triazenolysis of Alkenes: Aza-version of Ozonolysis DOI Creative Commons
Mark Gandelman, Alexander N. Koronatov, Pavel А. Sakharov

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Окт. 30, 2023

Abstract Numerous applications of alkenes exist due to their abundance and versatility in chemical transformations. In this study, we present a unique novel transformation alkenes, the aza-version canonical ozonolysis reaction, which termed as triazenolysis. This process offers non-trivial previously unfeasible synthetic disconnection, allowing cleavage C=C double bond into two new C-N bonds reductive manner. We carefully examined applicability finding that diverse cyclic are suitable for developed process. Furthermore, an example acyclic alkene, illustrating potential expanding triazenolysis other counterparts. Through DFT calculations, explored mechanism key step demonstrated significance Lewis acid catalysis achieving desired transformation.

Язык: Английский

Процитировано

0