Asymmetric cascades of the π-allyl complex: a journey from transition-metal catalysis to metallaphotocatalysis

Chemical Communications, Год журнала: 2023, Номер 59(76), С. 11298 - 11319

Опубликована: Янв. 1, 2023

The enantioselective catalytic cascade involving Tsuji-Trost allylation has provided a viable strategy for the construction of multiple asymmetric C-C and C-X centres numerous methods have been developed around it synthesis various vital scaffolds. synthetic utility this was enhanced by replacing customary allyl acetates with ethylene diacetates/dicarbonates, vinyl epoxides, oxetanes, carbonates, cyclopropanes, enynes, dienes using transition-metal catalysis. One more milestone achieved when metallaphotocatalysis necessary platform these cascades cheaper metal. This review will provide summary from 2015.

Язык: Английский

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Asymmetric synthesis of bicyclic pyran scaffolds bearing two oxa-quaternary stereocenters via zinc-catalyzed [5 + 1] annulations

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(18), С. 4516 - 4521

Опубликована: Янв. 1, 2023

Zinc-catalyzed [5 + 1] annulation of α-hydroxyl aryl ketones with cyclohexadienone-tethered enones has been developed, giving access to enantioenriched bicyclic pyran scaffolds bearing two oxa-quaternary stereocenters.

Язык: Английский

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Half-Sandwich d6-Metal (CoIII, RhIII, IrIII, RuII)-Catalyzed Enantioselective C–H Activation

SynOpen, Год журнала: 2023, Номер 07(04), С. 466 - 485

Опубликована: Сен. 6, 2023

Abstract Transition-metal-catalyzed enantioselective C–H activation provides a straightforward strategy to synthesize chiral molecules from readily available sources. In this graphical review, we summarize the progress on half-sandwich d6-metal (CoIII, RhIII, IrIII, RuII)-catalyzed functionalization reactions. The review is categorized according type of metal catalyst and ligand employed. Representative enantio-determining models catalytic cycles are presented.

Язык: Английский

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Synthesis of γ-Spirolactams via Rh(III)-Catalyzed C–H Activation/Directing Group Migration/Dearomatization/Spiroannulation of Indoles with 1,3-Enynes

Organic Letters, Год журнала: 2024, Номер 26(42), С. 8975 - 8981

Опубликована: Авг. 29, 2024

1,3-Enynes are valuable coupling partners in transition-metal-catalyzed C-H functionalizations. Certainly, aliphatic-substituted 1,3-enynes have been thoroughly investigated functionalizations, whereas aromatic-substituted remain underexplored. Herein, we report the realization of this goal, where achieve an atom-economical protocol for synthesis γ-spirolactams via Rh(III)-catalyzed functionalization

Язык: Английский

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Six-membered ring systems: Diazines and benzo derivatives

Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 355 - 393

Опубликована: Янв. 1, 2024

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