European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(42)
Опубликована: Сен. 5, 2023
Abstract
Metal‐free,
visible
light‐induced
difunctionalizations
of
α
‐CF
3
styrenes
with
aryl
diazonium
salts
and
various
hetero
nucleophiles
(ROH,
H
2
O,
N
−
F
)
are
described.
This
concise
protocol
provided
easy
access
to
the
tertiary
alkyl
ethers,
alcohol
fluorides
good
yields
excellent
functional
group
tolerance.
In
addition,
four‐component
“SO
”
insertion
reaction
also
worked
efficiently
produce
,
β
‐sulfonyl
ethers
in
moderate
yields.
A
radical‐polar
crossover
coupling
pathway
was
proposed
for
C−O
bond
formation.
Molecules,
Год журнала:
2024,
Номер
29(15), С. 3620 - 3620
Опубликована: Июль 31, 2024
Synthetic
radicals
have
intrinsic
power
for
cascading
and
multifunctional
reactions
to
construct
diverse
molecular
scaffolds.
In
the
previous
review
series,
we
covered
1,2-difunctionalizations,
remote
1,3-,
1,4-,
1,5-,
1,6-,
1,7-difunctionalizations,
addition
followed
by
cyclization
reactions,
cycloaddition-initiated
difunctionalizations.
Presented
in
this
paper
are
radical
addition-initiated
trifunctionalization
of
alkenes,
alkynes,
their
derivatives.
After
initial
addition,
there
different
pathways,
such
as
group
or
hydrogen
atom
transfer,
cyclization,
coupling,
complete
second
third
functionalizations.
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 5, 2024
A
TBADT-photocatalyzed
cascade
hydrogen
atom
transfer
procedure
was
established
for
the
synthesis
of
α-CF
3
-1,4-diketones
from
aldehydes
and
2-bromo-3,3,3-trifluoro-1-propenes.
Chemical Communications,
Год журнала:
2023,
Номер
59(51), С. 7986 - 7989
Опубликована: Янв. 1, 2023
From
a
single
alkene
to
two
different
alkenes!
An
iron-catalyzed
four-component
reaction
involving
an
aldehyde,
alkenes
and
TMSN3
is
developed
assemble
these
four
reactants
in
orderly
fashion
based
on
the
inherent
nucleophilic/electrophilic
activity
of
radicals
via
double
radical
addition,
providing
various
multifunctional
compounds
containing
azido
group
carbonyl
groups.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(42)
Опубликована: Сен. 5, 2023
Abstract
Metal‐free,
visible
light‐induced
difunctionalizations
of
α
‐CF
3
styrenes
with
aryl
diazonium
salts
and
various
hetero
nucleophiles
(ROH,
H
2
O,
N
−
F
)
are
described.
This
concise
protocol
provided
easy
access
to
the
tertiary
alkyl
ethers,
alcohol
fluorides
good
yields
excellent
functional
group
tolerance.
In
addition,
four‐component
“SO
”
insertion
reaction
also
worked
efficiently
produce
,
β
‐sulfonyl
ethers
in
moderate
yields.
A
radical‐polar
crossover
coupling
pathway
was
proposed
for
C−O
bond
formation.
