Photoactivated Formal [3 + 2] / [4+2] Cycloaddition of N‐Aryl Cyclopropyl and Cyclobutylamines DOI Creative Commons
Montserrat Zidan, Lucas F. Villela, Louis Barriault

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(44)

Опубликована: Окт. 24, 2024

Abstract Organic transformations initiated by photochemical activation have been at the forefront of reaction discovery. In this study, we present a formal [3+2] and [4+2] cycloaddition using N ‐aryl cyclopropylamines cyclobutylamines in conjunction with α , β ‐unsaturated carbonyl systems, unveiling two distinct mechanistic pathways. The is elucidated as being guided activity an electron donor‐acceptor (EDA) complex. Simultaneously, intermolecular annulation cyclobutylanilines achieved visible‐light photoredox catalysis. These simple methodologies wide applicability, facilitating synthesis ‐arylaminocycloalkyl compounds yields ranging from good to excellent.

Язык: Английский

Photocatalyzed de novo synthesis of fused tetracyclic skeletons via stepwise formal [3 + 2]/[4 or 5 + 2] cycloadditions DOI

Wenjing Guan,

Jinlin Hang,

Guanru Liu

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(23), С. 6712 - 6717

Опубликована: Янв. 1, 2024

A visible light-promoted synthesis route to fused tetracyclic skeletons with rich sp 3 carbons through stepwise radical cycloadditions and further cyclization of the final intermediates adjacent aromatic rings was developed.

Язык: Английский

Процитировано

1
Photoactivated Formal [3 + 2] / [4+2] Cycloaddition of N‐Aryl Cyclopropyl and Cyclobutylamines DOI Creative Commons
Montserrat Zidan, Lucas F. Villela, Louis Barriault

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(44)

Опубликована: Окт. 24, 2024

Abstract Organic transformations initiated by photochemical activation have been at the forefront of reaction discovery. In this study, we present a formal [3+2] and [4+2] cycloaddition using N ‐aryl cyclopropylamines cyclobutylamines in conjunction with α , β ‐unsaturated carbonyl systems, unveiling two distinct mechanistic pathways. The is elucidated as being guided activity an electron donor‐acceptor (EDA) complex. Simultaneously, intermolecular annulation cyclobutylanilines achieved visible‐light photoredox catalysis. These simple methodologies wide applicability, facilitating synthesis ‐arylaminocycloalkyl compounds yields ranging from good to excellent.

Язык: Английский

Процитировано

0