Generation of Carbamoyl Radicals and 3,4-Dihydroquinolin-2(1H)-ones Enabled by Iron Photoredox Catalysis

Synlett, Год журнала: 2024, Номер unknown

Опубликована: Май 16, 2024

Abstract A new protocol for accessing 3,4-dihydroquinolin-2(1H)-ones was established through a sequence of iron-catalyzed photoredox generation carbamoyl radicals from oxamic acids, addition the to electron-deficient alkenes, intramolecular cyclization, and aromatization. The process is compatible with variety N-phenyloxamic acids monosubstituted, 1,1-disubstituted, trisubstituted alkenes. Employing cheap, readily available, environmentally benign iron as catalyst, provides an excellent alternative synthesis 3,4-dihydroquinolin-2(1H)-ones.

Язык: Английский

Iron-catalyzed thiolation of C(sp³)–H with sulfonyl chlorides via photoinduced ligand-to-metal charge transfer

Organic Chemistry Frontiers, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A photoinduced FeCl 3 /HCl synergistic catalytic method enables C(sp )–S bond formation via reductive cross-coupling of activated/inert )–H and aryl/alkyl sulfonyl chlorides through ligand-to-metal charge transfer (LMCT).

Язык: Английский