Enantioselective Desymmetrization of 1,3‐Dicarbonyl Compounds through Transition‐Metal‐Catalyzed Intramolecular Cyclization Reactions DOI
Ren‐Xiao Liang, Jiaqi Xie,

Hu-Jie Cai

и другие.

ChemCatChem, Год журнала: 2024, Номер 16(20)

Опубликована: Июль 1, 2024

Abstract The development of reliable approaches to construct enantioenriched cyclic ketones bearing multiple stereocenters has attracted intense interest in synthetic chemistry, yet remains a challenging research area due the difficulties efficiently controlling reaction enantioselectivity and diastereoselectivity. Desymmetrization C2‐symmetric prochiral substrates witnessed practical accessible strategy for creating more than one single operation. In recent years, enantioselective desymmetrization 1,3‐dicarbonyl compounds been developed via transition‐metal‐catalyzed transformations facile assembly optically active congested with diverse functionality. this review, we would like describe intramolecular reactions derivatives, including C2‐functional group tethered 1,3‐diketones 1,3‐diesters. This review is organized according types groups, which aims highlight advances briefly discuss about future perspectives domain.

Язык: Английский

Enantioselective Desymmetrization of 1,3‐Dicarbonyl Compounds through Transition‐Metal‐Catalyzed Intramolecular Cyclization Reactions DOI
Ren‐Xiao Liang, Jiaqi Xie,

Hu-Jie Cai

и другие.

ChemCatChem, Год журнала: 2024, Номер 16(20)

Опубликована: Июль 1, 2024

Abstract The development of reliable approaches to construct enantioenriched cyclic ketones bearing multiple stereocenters has attracted intense interest in synthetic chemistry, yet remains a challenging research area due the difficulties efficiently controlling reaction enantioselectivity and diastereoselectivity. Desymmetrization C2‐symmetric prochiral substrates witnessed practical accessible strategy for creating more than one single operation. In recent years, enantioselective desymmetrization 1,3‐dicarbonyl compounds been developed via transition‐metal‐catalyzed transformations facile assembly optically active congested with diverse functionality. this review, we would like describe intramolecular reactions derivatives, including C2‐functional group tethered 1,3‐diketones 1,3‐diesters. This review is organized according types groups, which aims highlight advances briefly discuss about future perspectives domain.

Язык: Английский

Процитировано

0