Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 123 - 173
Опубликована: Янв. 1, 2024
Язык: Английский
The Chemical Record, Год журнала: 2025, Номер unknown
Опубликована: Янв. 16, 2025
Abstract Selectfluor, [1‐chloromethyl‐4‐fluoro‐1,4‐diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)], is a highly valuable reagent in contemporary chemistry, serving not only as an electrophilic fluorinating agent but also effective catalyst the synthesis of various pharmaceutically relevant heterocycles. This review article seeks to present comprehensive overview significant heterocyclic ring formations facilitated by selectfluor. Both metal‐free and metal‐catalyzed recent advancement on selectfluor mediated cyclisation processes are discussed this mainly over last eight years (2017‐April 2024).
Язык: Английский
Процитировано
1
Chemical Reviews, Год журнала: 2025, Номер unknown
Опубликована: Апрель 22, 2025
Fluorine and nitrogen form a successful partnership in organic synthesis, medicinal chemistry, material sciences. Although fluorine-nitrogen chemistry has long rich history, this field received increasing interest made remarkable progress over the past two decades, driven by recent advancements transition metal organocatalysis photochemistry. This review, emphasizing contributions from 2015 to 2023, aims update state of art synthesis applications nitrogen-based organofluorine functional molecules chemistry. In dedicated sections, we first focus on fluorine-containing reagents organized according type groups attached nitrogen, including N-F, N-RF, N-SRF, N-ORF. review also covers nitrogen-linked building blocks, catalysts, pharmaceuticals, agrochemicals, underlining these components' broad applicability growing importance modern
Язык: Английский
Процитировано
1
Journal of the American Chemical Society, Год журнала: 2024, Номер 146(28), С. 18841 - 18847
Опубликована: Июль 8, 2024
An asymmetric intramolecular spiro-amination to high steric hindering
Язык: Английский
Процитировано
5
Chinese Journal of Organic Chemistry, Год журнала: 2025, Номер 45(2), С. 694 - 694
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(7), С. 2075 - 2080
Опубликована: Янв. 1, 2024
A dppb and TfOH promoted cascade reaction of o -nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls under mild conditions is developed.
Язык: Английский
Процитировано
1
Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(10), С. 2815 - 2820
Опубликована: Янв. 1, 2024
An interesting diazenylation reaction is demonstrated, which enables the efficient synthesis of hydrazones using active methyne compounds and arylazo sulfones.
Язык: Английский
Процитировано
0
European Journal of Organic Chemistry, Год журнала: 2024, Номер unknown
Опубликована: Май 24, 2024
Abstract The efficient synthesis of an array 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols in a one‐pot epoxidation/nucleophilic ring‐opening via the corresponding iodohydrines is described. This methodology permits construction 1,1‐difluorinated derivatives commercialized beta‐blockers addition to unprecedented members this compound class.
Язык: Английский
Процитировано
0
Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(20), С. 4244 - 4252
Опубликована: Май 25, 2024
Abstract A strategy to access fluorinated spiroindolenines has been developed, involving a selective functionalization of indoles with moieties and subsequent catalytic dearomatization. Trifluomethylthio (SCF 3 ), diethyl phosphono(difluoromethyl)thio 2 P(O)(OEt) ) (phenylsulfonyl)difluoromethyl (CF SO Ph) groups were embedded at the C2 position indole derivatives substituted alkynes, allenes, allyl carbonate C3 position. gold‐catalyzed cycloisomerization gave five spiroindolenines, an enantioselective palladium catalyzed cyclization provided 10 spirocyclic products up 77% ee.
Язык: Английский
Процитировано
0
Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 123 - 173
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0