Recent Advances in Photochemical/Electrochemical Carboxylation of Olefins with CO2
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
42(18), С. 2249 - 2266
Опубликована: Май 15, 2024
Comprehensive
Summary
CO
2
is
an
abundant,
nontoxic,
and
renewable
C1
feedstock
in
synthetic
chemistry.
Direct
carboxylation
of
readily
available
olefins
incorporating
regarded
as
a
promising
strategy
to
access
high
value‐added
carboxylic
acids
well
fixation.
However,
due
the
thermodynamic
stability
kinetic
inertness
difficulty
controlling
regioselectivity,
with
still
remains
challenging.
Radical‐type
functionalization
represented
powerful
protocol
enabled
development
novel
transformations
this
realm.
More
recently,
advance
new
technology,
such
photoredox
catalysis
renaissance
electrochemistry
organic
synthesis,
offered
unique
chemical
reactivities
radical
precursors
provided
solutions
olefins.
This
review
presents
recent
advances
radical‐type
olefins,
which
has
mainly
been
achieved
through
photocatalysis
electrocatalysis
last
decade.
In
article,
we
provide
comprehensive
introduction
progress,
summarize
advantages
limitations
current
research,
discuss
potential
outlook
for
further
development.
Key
Scientists
Язык: Английский
Visible-Light-Induced Redox-Neutral Difunctionalization of Alkenes and Alkynes
Chemical Communications,
Год журнала:
2024,
Номер
60(72), С. 9659 - 9691
Опубликована: Янв. 1, 2024
The
twelve
principles
of
green
chemistry
illuminate
the
pathway
in
direction
sustainable
and
eco-friendly
synthesis,
marking
a
fundamental
shift
synthetic
organic
paradigms.
In
this
realm,
harnessing
power
visible
light
for
difunctionalization
various
skeletons
without
employing
any
external
oxidant
or
reductant,
specifically
termed
as
redox-neutral
difunctionalization,
has
attracted
tremendous
interest
from
chemists
due
to
its
low
cost,
easy
availability
environmentally
friendly
nature
contrast
traditional
metal-catalyzed
difunctionalizations.
This
review
presents
an
overview
recent
updates
on
visible-light-induced
reactions
with
literature
coverage
up
May
2024.
Язык: Английский
Unveiling Heavier Dihydropyridine Chalcogenol Esters in Metallaphotoredox Catalyst-Enabled Regioselective Hydrothio(seleno)carbonylation
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 23, 2025
Herein,
aromaticity-driven
thio(seleno)ester
group
transfer
from
novel
1,4-dihydropyridine
thio(seleno)esters
to
alkene
feedstocks
is
disclosed
by
merging
palladium
and
photoredox
catalysis.
In
this
process,
photoactivation
of
dihydropyridine
integrated
with
regioselective
hydrometalation
alkenes,
avoiding
photoinduced
Pd-C
bond
homolysis
organopalladium
intermediates.
Additionally,
a
hydroselenocarbonylation
an
accomplished
for
the
first
time
using
bench-stable
selenoester
reagent.
The
activation
mode
thioesters
has
been
illustrated
detailed
mechanistic
studies,
spectroscopic
analysis,
intermediate
trapping,
isotope
labeling
experiments.
Язык: Английский
Alkene Carboxy-Alkylation via CO2•–
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(51), С. 35035 - 35042
Опубликована: Дек. 12, 2024
Herein,
we
introduce
a
new
platform
for
alkene
carboxy-alkylation.
This
reaction
is
designed
around
CO
Язык: Английский
Photocatalytic Pyridyl-carbamoylation of Alkenes for Accessing β-Pyridyl Amides
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 7, 2025
The
β-pyridyl
amide
is
a
critical
scaffold
in
medical
discovery
yet
lacks
efficient
synthetic
methods.
Here,
we
describe,
for
the
first
time,
visible-light-induced,
redox-neutral
radical
cross-coupling
reaction
involving
alkenes,
oxamic
acids,
and
cyanopyridines
that
offers
versatile
assembly
of
β-pyridylamides.
This
approach
features
mild
conditions,
high
step
efficiency,
substrate
breadth,
providing
green
strategy
alkene
pyridyl-carbamoylation.
Achieving
this
transformation
relies
on
catalytic
system,
which
adeptly
avoids
competing
nucleophilic
carbamoyl
with
electrophilic
pyridyl
radical,
enabling
three-component
tandem
process
chemoselectivity.
Язык: Английский
Photocatalytic Multicomponent Carboxylation of Olefins and Sulfinate Salts with 13CO2
ACS Catalysis,
Год журнала:
2024,
Номер
unknown, С. 18633 - 18638
Опубликована: Дек. 6, 2024
Herein,
we
describe
a
photoinduced
multicomponent
catalytic
carboxylation
protocol
that
streamlines
the
access
to
13C-labeled
carboxylic
acids
from
simple
olefin
precursors,
sulfinate
salts
and
13CO2.
Site
selectivity
is
dictated
by
radical
philicity
of
starting
precursors
reaction
intermediates,
resulting
in
either
four-component
or
five-component
endeavor.
The
method
characterized
its
simplicity
flexibility
across
wide
number
coupling
counterparts
Язык: Английский