Palladium-Catalyzed Dual-Tasked ortho-C–H Borylation of Aryl Iodides DOI
Shuai Yang, Fanyi Meng, Yanghui Zhang

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 5, 2024

The Pd-catalyzed ortho-C–H borylation of aryl iodides has been developed through maleimide-relayed C–H activation. In this reaction, the ipso-positions and bonds are alkylated borylated, respectively, providing a new strategy for borylation. reaction exhibits broad substrate scope represents modular synthetic method functionalized 3-aryl succinimides, which essential structural motifs in organic compounds with diverse biological activities. Furthermore, boronate group can be further manipulated, practical utility demonstrated. This work also introduces ipso, ortho-difunctionalization halides via

Язык: Английский

Advances in Palladium-Catalyzed C(sp3)–H Functionalization: The Role of Traceless Directing Groups DOI
Masoud Sadeghi

ACS Catalysis, Год журнала: 2024, Номер unknown, С. 15356 - 15373

Опубликована: Окт. 3, 2024

Язык: Английский

Процитировано

8
Ligand-Enabled Palladium-Catalyzed [3 + 2] Annulation of Aryl Iodides with Maleimides via C(sp3)–H Activation DOI

Wei Feng,

Yanghui Zhang

Organic Letters, Год журнала: 2024, Номер 26(29), С. 6209 - 6213

Опубликована: Июль 12, 2024

Palladium-catalyzed intermolecular [3 + 2] annulation reactions via C-H activation represent a powerful and charming tool for assembling cyclopentanes. Herein, we have developed strategy the palladium-catalyzed alkene-relayed reaction of aryl iodides maleimides C(sp

Язык: Английский

Процитировано

5
Dual C(sp3)–H and C(sp2)–H Activation of 8-Methylquinoline N-Oxides: A Route to Access C7–H Bond DOI
Santu Mandal,

Madhab Barman,

Bijoy Debnath

и другие.

Organic Letters, Год журнала: 2024, Номер 26(36), С. 7560 - 7564

Опубликована: Сен. 4, 2024

A Pd(II)-catalyzed regioselective dual C(sp

Язык: Английский

Процитировано

1
Late-Stage Modification of Peptides with Maleimides through Palladium-Catalyzed β-C(sp3)–H Alkylation DOI

Fengjie Lu,

Yujie Geng,

Huihui Wang

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Окт. 4, 2024

Transition-metal-catalyzed C-H activation has proven to be a powerful tool for the late-stage modification of peptides. We herein report method site-selective alkylation peptides with maleimides through Pd-catalyzed β-C(sp

Язык: Английский

Процитировано

1
Synthesis of Aza‐Bicyclic Maleimide Skeleton by Addition‐Ring Opening Cascade Reaction of Vinylogous Oxindole DOI
Qian Liao, Yang Zhang, Jin‐Yu Liu

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(20)

Опубликована: Апрель 1, 2024

Abstract An efficient method has been developed to facilitate the addition‐ring opening cascade reaction of vinylogous oxindole, resulting in synthesis a variety aza‐bicyclic maleimide derivatives with high yields and exceptional diastereoselectivities. Furthermore, product could be effectively easily transformed into difluoromethylenecyclohexane skeleton through dehydrofluorination process. This methodology demonstrates significant potential for skeleton, which possesses biological or pharmaceutical activity.

Язык: Английский

Процитировано

0
Palladium-Catalyzed Dual-Tasked ortho-C–H Borylation of Aryl Iodides DOI
Shuai Yang, Fanyi Meng, Yanghui Zhang

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 5, 2024

The Pd-catalyzed ortho-C–H borylation of aryl iodides has been developed through maleimide-relayed C–H activation. In this reaction, the ipso-positions and bonds are alkylated borylated, respectively, providing a new strategy for borylation. reaction exhibits broad substrate scope represents modular synthetic method functionalized 3-aryl succinimides, which essential structural motifs in organic compounds with diverse biological activities. Furthermore, boronate group can be further manipulated, practical utility demonstrated. This work also introduces ipso, ortho-difunctionalization halides via

Язык: Английский

Процитировано

0