Visible-Light-Induced Decarboxylative Annulation of α,β-Unsaturated Acids with Amines and α-Keto Acids for 2,4-Diarylquinoline Synthesis
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 3, 2025
An
efficient
and
sustainable
approach
for
the
synthesis
of
2,4-diarylquinolines
has
been
developed
via
a
visible-light-promoted
metal-free
three-component
decarboxylative
annulation
pathway.
This
one-pot
protocol
combines
readily
available
feed-stock
α,β-unsaturated
acids,
aromatic
amines,
α-keto
acids
in
cascade
manner
to
access
substituted
quinolines
under
eco-benign
conditions.
Moreover,
mechanistic
insights
suggest
initial
C-C
cross
coupling
followed
by
6π
electrocyclic
afford
desired
products.
The
broad
substrates
scope
excellent
functional
group
tolerance
make
this
more
attractive
synthetically
applicable
toward
construction
complex
N-heterocycles.
Язык: Английский
Light-induced ligand-to-metal charge transfer of Fe(III)-OR species in organic synthesis
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(30), С. 6034 - 6044
Опубликована: Янв. 1, 2024
This
review
highlights
studies
on
ligand-to-metal
charge
transfer
of
Fe(
iii
)-OR
species
in
organic
transformations.
Язык: Английский
Photocatalytic decarboxylation of free carboxylic acids and their functionalization
Subal Mondal,
Subham Mandal,
Soumya Mondal
и другие.
Chemical Communications,
Год журнала:
2024,
Номер
60(72), С. 9645 - 9658
Опубликована: Янв. 1, 2024
This
highlight
article
summarizes
the
complete
development
of
photodecarboxylative
functionalization
free
carboxylic
acids
via
a
concerted
single
electron
transfer
(SET)
or
energy
(ET)
pathways.
Язык: Английский
Iron‐Catalyzed, Light‐Driven Decarboxylative Alkoxyamination
Milan Innocent,
Clément Tanguy,
Sigrid Gavelle
и другие.
Chemistry - A European Journal,
Год журнала:
2024,
Номер
30(41)
Опубликована: Май 13, 2024
An
iron-catalyzed
visible-light
driven
decarboxylative
alkoxyamination
is
disclosed.
In
the
presence
of
FeBr
Язык: Английский
Visible-Light-Promoted Iron(II)/Lewis Base Catalysis for the Alkylation of Morita–Baylis–Hillman Acetates Using Carboxylic Acids
Durga Golagani,
Kota Krishna Prakash,
Satyam Thapa
и другие.
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
A
novel
photoinduced
Fe(OTf)
Язык: Английский
Iron-Catalyzed Multicomponent C–H Alkylation of in Situ Generated Imines via Photoinduced Ligand-to-Metal Charge Transfer
Organic Letters,
Год журнала:
2024,
Номер
26(30), С. 6347 - 6352
Опубликована: Июль 22, 2024
Herein,
we
describe
a
novel
photoinduced
iron-catalyzed
strategy
for
multicomponent
C-H
alkylation
of
in
situ
generated
imines.
By
utilizing
the
alkyl
radicals
through
iron-mediated
photocatalytic
activation,
imines
formed
are
further
subjected
to
addition
reactions,
resulting
synthesis
various
secondary
and
tertiary
amine
products.
This
method
is
simple
operate
does
not
require
additional
oxidants.
It
applicable
inert
alkane
substrates
such
as
cyclic
alkanes,
ethers,
toluene,
ketones.
The
reaction
also
compatible
with
aromatic
amines,
halogenated
well
aldehydes,
cinnamaldehyde,
among
other
different
types
aldehydes.
Язык: Английский
Iron-Photocatalyzed Decarboxylative Alkylation of Carboxylic Acids with Morita–Baylis–Hillman Acetates
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 27, 2024
We
present
an
iron-photocatalyzed
decarboxylative
alkylation
strategy
involving
carboxylic
acids
and
Morita–Baylis–Hillman
(MBH)
acetates
to
synthesize
E-type
tri-
tetrasubstituted
alkenes
with
moderate
excellent
stereoselectivity
(E/Z
ratio
up
>19:1).
This
method
is
applicable
a
broad
range
of
structurally
diverse
primary,
secondary,
tertiary
alkyl
acids,
as
well
complex
pharmaceutical
natural
achieving
efficient
various
MBH
under
mild
conditions
(>60
examples,
yields
96%).
approach
offers
powerful
for
streamlined
alkylation.
Язык: Английский