N‐Heterocyclic Carbene/Transition Metal Dual Catalysis
Chemistry - A European Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 17, 2024
Abstract
N‐heterocyclic
carbene
catalysis
has
been
developed
as
a
versatile
method
for
the
enantioselective
synthesis
of
complex
organic
molecules
in
chemistry.
Merging
with
transition
metal
holds
potential
to
achieve
unprecedented
transformations
broad
substrate
scope
and
excellent
stereoselectivity,
which
are
unfeasible
individual
catalyst.
Thus,
this
dual
attracted
increasing
attention,
numerous
elegant
catalytic
systems
have
established.
In
review,
we
summarize
recent
achievements
NHC/transition
catalysis,
including
reaction
design,
mechanistic
studies
practical
applications.
Язык: Английский
Regioselective Alkylacylation of 1,3-Dienes by Merging N-Heterocyclic Carbene Catalysis with Photoinduced Palladium Catalysis
Organic Letters,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 17, 2024
Herein,
we
develop
a
dual
catalytic
platform
for
the
1,2-
or
1,4-alkylacylation
reaction
of
1,3-dienes
with
readily
available
alkyl
halides
and
aldehydes
by
merging
N-heterocyclic
carbene
catalysis
photoinduced
palladium
catalysis.
A
series
β,γ-unsaturated
ketones
are
obtained
in
good
to
high
yields.
Mechanistic
studies
suggest
that
this
involves
radical
process.
The
direct
synthesis
flavanone
from
salicylaldehyde
exemplified
potential
capability
platform.
Язык: Английский
anti-Selective Carboacylation of Alkynes via Photoredox/Nickel Dual Catalysis
Xianhua Pan,
Chang-Xin Shi,
Ya-Ping Hou
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(44), С. 9498 - 9502
Опубликована: Окт. 31, 2024
Here,
we
report
an
intermolecular
carboacylation
of
terminal
alkynes
with
tertiary
and
secondary
alkyltrifluoroborates
as
well
acyl
chlorides
via
photoredox/nickel
dual
catalysis,
affording
a
varity
stereodefined
trisubstituted
enones
in
good
to
excellent
yields
E
stereoselectivity,
through
radical
relay
process.
This
redox-neutral
protocol
exhibits
functional
group
tolerance,
exclusive
regio-
broad
compatibility
various
alkyltrifluoroborates.
Язык: Английский