Organic Letters, Год журнала: 2024, Номер unknown
Опубликована: Дек. 16, 2024
N-Enoxyimides are versatile and valuable synthetic synthons in modern organic synthesis catalysis. Herein, a silver-catalyzed hydrooxyimidation of terminal alkynes that enables the N-enoxyimides, has been demonstrated. The protocol features simple, step- atom-efficient, scalable, exhibit broad scope functional group tolerance under mild conditions. A novel hydrolysis N-enoxyimides unexpectedly provides corresponding aromatic oximes 96% yield, showing potential application this strategy.
Язык: Английский