Arylation of α‐Imino Ketones and their Cyclization with Allenoates: Direct Access to Sterically Hindered Pyrroles
Asian Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 28, 2025
Abstract
Herein,
we
report
a
calcium‐catalyzed,
one‐pot,
four‐component
reaction
to
synthesize
diversely
substituted
pyrroles.
This
atom‐economy
involves
sequence
of
reactions
that
proceed
via
in
situ
formation
α
‐
imino
ketones,
Friedel‐Crafts
arylation,
aza‐cyclization,
and
aromatization
the
single
pot.
The
showed
broad
substrate
scope
with
good
yields.
We
demonstrated
gram‐scale
synthesis
post‐synthetic
modifications.
Язык: Английский
Rh(III)-Catalyzed Redox-Neutral C–H Activation/Annulation of Oxadiazolones with Sulfoxonium Ylides to access oxadiazoloisoquinolinone
Pothapragada S. K. Prabhakar Ganesh,
Eswaran Kamaraj,
Vairaperumal Veeramani
и другие.
New Journal of Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Oxadiazolone-fused
isoquinolines
were
synthesized
via
Rh(
iii
)-catalyzed
[4+2]
annulation
and
C–H
activation,
followed
by
acymethylation
products
with
antidiabetic
anti-inflammatory
potential.
Язык: Английский
Acetoxy allenoates as emerging synthons in annulation/cycloaddition reactions
Chemical Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
The
emergence
of
acetoxy
allenoates
as
versatile
synthons
to
generate
a
plethora
annulation/cycloaddition
products
via
electrophilic
diene–phosphonium/ammonium
intermediates
is
highlighted
in
this
feature
article.
Язык: Английский