Iodonium(III) Ylide: An Iodoalkylation Reagent with Aryne
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 5, 2025
A
tandem
Hexadehydro-Diels–Alder
(HDDA)/[2
+
2]
cycloaddition/aryl
migration
reaction
of
iodonium
ylide
with
tetrayne
is
described,
in
which
served
as
a
unique
double
bond
and
reacted
aryne
to
form
four-membered
iodonium(III)
cycle,
then
converted
iodoarene
after
aryl
group
from
iodine
adjacent
carbon.
This
strategy
allows
the
efficient
construction
fully
substituted
compounds.
Язык: Английский
Rh-Catalyzed Coupling of Cyclic 1,3-Dicarbonyl-Derived Iodonium Ylides with Cyclopropanols
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 10, 2025
Herein,
we
report
a
modular
α-monoalkylation
of
cyclic
1,3-dicarbonyls
with
cyclopropyl
alcohols
through
iodonium
ylide
strategy.
This
approach
is
general,
base-free,
operationally
simple,
and
suitable
for
various
medically
important
(hetero)cyclic
1,3-dicarbonyls.
A
wide
range
alcohols,
easily
prepared
from
feedstock
chemicals,
can
serve
as
complement
alkylating
agents.
Importantly,
the
newly
formed
carbonyl
groups
in
resulting
products
provide
versatile
platform
numerous
synthetic
applications.
Язык: Английский
Tunable Rh(III)-Catalyzed C(sp2)–H Bond Functionalization of Aryl Imidates with Cyclic 1,3-Diones: Strategic Use of Directing Groups
Organic Letters,
Год журнала:
2024,
Номер
26(37), С. 7885 - 7890
Опубликована: Сен. 6, 2024
A
tunable
Rh(III)-catalyzed
C(sp
Язык: Английский
Cyclic Iodonium Ylide Unlocked Pd-Catalyzed α-Acyloxylation of Cyclic 1,3-Dicarbonyls with Carboxylic Acids
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 10, 2024
To
date,
a
general
approach
for
the
direct
α-acyloxylation
of
cyclic
1,3-dicarbonyls
remains
challenging.
Herein,
we
report
Pd-catalyzed
1,3-dicarbonyl-derived
hypervalent
iodine
compounds
with
highly
abundant
carboxylic
acids.
Our
utilizes
commercially
available
Pd(OAc)
Язык: Английский
Bioinspired Synthesis of Phelligridin Analogues via Ru-Catalyzed C–H Activation/[4 + 2] Annulation of Aryl Imidates with Heteroaromatic Iodonium Ylides
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 16, 2024
The
first
Ru(II)-catalyzed
C–H
activation/[4
+
2]
annulation
of
aryl
imidates
with
heteroaromatic
iodonium
ylides
is
reported.
Our
approach
features
the
utilization
a
commercially
available
ruthenium
catalyst,
providing
one-step
construction
phelligridin
analogues
from
easily
and
nonpreactivated
starting
materials.
developed
methodology
successfully
employed
for
total
synthesis
A,
significantly
streamlining
previous
multistep
synthesis.
potential
this
further
demonstrated
through
modular
core
structure
C/D.
Язык: Английский