Electrochemical Deaminative Carboxylation of Aryltriazenes with CO2 to Aryl Carboxylic Acids
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 18, 2025
The
utilization
of
CO2
as
an
appealing
chemical
feedstock
for
diverse
synthetically
valuable
products
is
constantly
evolving,
potentially
alleviating
production
that
relies
on
petrochemistry.
Herein
we
report
the
first
example
electrochemical
deaminative
carboxylation
aryltriazenes
with
CO2.
reaction
can
be
performed
under
mild
and
catalyst-free
conditions
by
using
sustainable
methods
a
green
C1
building
block,
efficiently
converting
range
readily
available
into
carboxylic
acids.
In
particular,
formation
C-C
bonds
would
impactful
addition
to
synthesis
toolbox.
Язык: Английский
Iodide/Nickel Co-Catalyzed Manganese-Mediated Denitrogenative Cross-Electrophile Coupling of Benzotriazinones with Alkyl Sulfonates
Yingying Hong,
Xuanxuan Zhang,
Gang Zou
и другие.
Molecules,
Год журнала:
2025,
Номер
30(11), С. 2397 - 2397
Опубликована: Май 30, 2025
An
efficient
Ni-catalyzed,
Mn-mediated
denitrogenative
cross-electrophile
coupling
of
N-alkyl-1,2,3-benzotriazinones
with
alkyl
tosylates
and
mesylates
for
access
to
o-alkyl
secondary
benzamides
is
reported.
The
method
uses
inexpensive
non-anhydrous
dimethyl
acetamide
(DMA)
in
combination
tetrabutyl
ammonium
iodide
(TBAI)
as
a
co-catalyst
convert
sulfonates
into
iodides
situ.
Scope
limitations
the
protocol
have
been
demonstrated
by
>30
examples
yields
up
91%,
showing
large
electronic
effect
from
N-substituent
benzotriazinones.
unexpected
steric
acceleration
has
observed
core
benzotriazinones,
not
only
promising
highly
2-alkyl-2,3-disubstituted
but
also
shedding
light
on
rate-limiting
steps
catalytic
cycle.
Язык: Английский