Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO3 and Alcohols
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 7, 2024
Comprehensive
Summary
Alkenylsulfonates
are
commonly
encountered
in
medicinal
chemistry,
polymer
and
organic
synthesis.
In
this
research,
an
electrochemical
reaction
involving
alkynes,
NaHSO
3
,
alcohols
has
been
developed.
This
method
yields
functionalized
alkenylsulfonates
good
with
broad
functional
group
tolerance.
Mechanism
studies
indicate
that
anodic
oxidation
of
inorganic
sulfite,
radical
insertion
process,
HAT
process
involved
transformation.
Язык: Английский
Manganaelectro-Catalyzed Cyclization of o-Aminoarylketones with Ammonia: An Approach to 1,2-Dihydroquinazolines
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 12, 2024
A
manganaelectro-catalyzed
cyclization
reaction
of
2-aminoarylketones
with
simple
alcohols
and
ammonia
under
mild
conditions
is
reported
for
the
first
time.
The
cooperative
catalysis
effectively
enhances
oxidation
primary
into
aldehydes,
thus
enabling
synthesis
substituted
1,2-dihydroquinazolines
in
good
to
excellent
yields.
In
addition,
utilities
this
method
are
highlighted
construction
biologically
active
molecules
that
would
otherwise
be
difficult
access
through
a
traditional
method.
Язык: Английский
Substrate-Controlled Electrochemical Reaction of 2-Alkynylbenzamides, Inorganic Sulfites, and Alcohols
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
89(22), С. 16873 - 16882
Опубликована: Ноя. 6, 2024
Isoindolones
constitute
a
dominant
structural
class
in
synthetic
and
medicinal
chemistry.
In
this
research,
an
electrochemical
reaction
involving
2-alkynylbenzamides,
inorganic
sulfites,
alcohols
was
first
established
to
provide
sulfonyl
ester-substituted
3-hydroxyisoindolinone
derivatives
moderate
good
yields
with
excellent
functional
group
tolerance.
When
bulky
aryl-substituted
2-alkynylbenzamides
are
utilized
as
substrates,
3-alkylideneisoindolinones
can
be
selectively
generated
chemoselectivity.
Alkoxysulfonyl
radicals
derived
from
the
anodic
oxidation
of
sulfite
involved
transformation.
Язык: Английский