SNAr Hexafluoroisopropoxylation of Electron-rich Aryl Fluoride with a Catalytic Electrical Input DOI
Eisuke F. Sato,

Tatsuo Nakahama,

Koichi Mitsudo

и другие.

Chemistry Letters, Год журнала: 2024, Номер 53(11)

Опубликована: Окт. 22, 2024

Abstract Anodic oxidation–promoted SNAr reactions of electron-rich aryl fluoride were developed. The anodic oxidation 4-fluoroanisole in hexafluoroisopropyl alcohol (HFIP) with K2CO3 led to SNAr-type hexafluoroisopropoxylation, and the reaction was completed a catalytic electrical input. results cyclic voltammetry suggest that radical cation 4-fluoroanisole, which would react alkoxide HFIP, is generated. Electron transfer between intermediate starting material constructs cycle, elimination from Meisenheimer complex produces desired compound.

Язык: Английский

SNAr Hexafluoroisopropoxylation of Electron-rich Aryl Fluoride with a Catalytic Electrical Input DOI
Eisuke F. Sato,

Tatsuo Nakahama,

Koichi Mitsudo

и другие.

Chemistry Letters, Год журнала: 2024, Номер 53(11)

Опубликована: Окт. 22, 2024

Abstract Anodic oxidation–promoted SNAr reactions of electron-rich aryl fluoride were developed. The anodic oxidation 4-fluoroanisole in hexafluoroisopropyl alcohol (HFIP) with K2CO3 led to SNAr-type hexafluoroisopropoxylation, and the reaction was completed a catalytic electrical input. results cyclic voltammetry suggest that radical cation 4-fluoroanisole, which would react alkoxide HFIP, is generated. Electron transfer between intermediate starting material constructs cycle, elimination from Meisenheimer complex produces desired compound.

Язык: Английский

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