Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones DOI Creative Commons
Mohsen Monirialamdari,

Aleksandra Podlaska,

Dominika Pomikło

и другие.

ChemistryOpen, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 16, 2024

Abstract Electrochemically induced, decarboxylative functionalization of chromone‐3‐carboxylic acids by N ‐hydroxyphthalimide esters as alkyl radical precursors was studied. Electrochemical protocol offers a sustainable and green approach, obviating the need for catalysts, relying on direct reduction NHPI using electric current. Developed provides straightforward route to synthesis diverse molecules with potential biological activity.

Язык: Английский

Visible Light-Induced C–H Alkylation of Azauracils with N-Hydroxyphthalimide Esters via Catalytic EDA Complex DOI
Zhiqiang Zhu,

Wenyi Zhang,

Xiao‐Long Huang

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Herein, we report sodium iodide (NaI)-catalyzed decarboxylative C–H alkylation of azauracils with N-hydroxyphthalimide (NHPI) esters facilitated by visible light activation catalytic electron donor–acceptor (EDA) complexes. Control experiments and density functional theory calculations suggest that the coupling reaction proceeds via a transiently assembled EDA complex between NHPI ester NaI in N,N-dimethylacetamide solvent. This synthetic method efficiently applies to primary, secondary, tertiary under mild, photocatalyst-free, redox-neutral conditions, achieving high yields desired alkylated azauracils.

Язык: Английский

Процитировано

1
Electroreductively driven C–H functionalization of arenes DOI
Pengfei Xie,

Anzai Shi,

Youai Qiu

и другие.

Chem Catalysis, Год журнала: 2025, Номер unknown, С. 101359 - 101359

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Electrochemical Synthesis of Ketones Via Metal-Free Decarboxylative Coupling of Vinyl Azides and Nhpi Esters DOI
Siddharth Sharma,

Bhawana Jat

Опубликована: Янв. 1, 2025

We introduce a metal-free method for C–C bond formation by coupling NHPI esters with vinyl azides through electrochemical synthesis. By converting carboxylic acids into radical-initiating esters, our approach achieves efficient C(sp3)–C(sp3) without the need metal catalysts. This is highly adaptable, enabling of various broad range azides, including those halide or heteroatom substitutions. It offers sustainable to synthesizing complex molecules.

Язык: Английский

Процитировано

0
The organophotocatalytic trifluoromethylation of 6-azauracils DOI Creative Commons

Krishna Kanta Das,

Alakananda Hajra

RSC Advances, Год журнала: 2025, Номер 15(15), С. 11370 - 11376

Опубликована: Янв. 1, 2025

Herein, we have developed an organophotocatalytic trifluoromethylation of 6-azauracils using inexpensive Langlois reagent to prepare a variety trifluoromethylated azauracil derivatives under ambient air condition.

Язык: Английский

Процитировано

0
Benzothiazolines Acting as Carbanion and Radical Transfer Reagents in Carbon–Carbon Bond Construction DOI Creative Commons
Xiaotang Chen,

Bao‐Chen Qian

Molecules, Год журнала: 2025, Номер 30(8), С. 1711 - 1711

Опубликована: Апрель 11, 2025

Traditionally employed as hydrogenation reagents, benzothiazolines have emerged versatile carbanion and radical transfer playing a vital role in the construction of various carbon-carbon bonds. The cutting-edge progress photochemistry chemistry prompted study visible light-driven reactions, bringing into vibrant focus. Their chemical processes been uncovered to encompass variety activation mechanisms, with five distinct modes having identified. This work reviews innovative applications donors alkyl or acyl groups, achieving hydroalkylation hydroacylation substitution. By examining their diverse this review highlights potential serving groups for further research development. Moreover, will offer exemplary inspiration synthetic chemists, contributing ongoing evolution utility organic synthesis.

Язык: Английский

Процитировано

0
Recent Advances in Electrochemical Utilization of NHPI Esters DOI

Bhawana Jat,

Dinesh Kumar Yadav, Satpal Singh Badsara

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

This review highlights recent progress in the electrochemical use of NHPI esters for sustainable C–C and C–X bond formation under both metal-catalyzed metal-free conditions.

Язык: Английский

Процитировано

0
Silver-catalyzed direct decarboxylative C H functionalization of azauracils with aliphatic carboxylic acids DOI
Jie Zeng, Hong Zhou, Shenghao Wang

и другие.

Tetrahedron Letters, Год журнала: 2025, Номер unknown, С. 155619 - 155619

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Electricity-driven reductive coupling reaction of imines with N-(acyloxy)phthalimides DOI

X. Liu,

Leilei Feng

Tetrahedron Letters, Год журнала: 2024, Номер 153, С. 155367 - 155367

Опубликована: Ноя. 14, 2024

Язык: Английский

Процитировано

0
Electrochemically Induced, Metal Free Synthesis of 2‐substituted chroman‐4‐ones DOI Creative Commons
Mohsen Monirialamdari,

Aleksandra Podlaska,

Dominika Pomikło

и другие.

ChemistryOpen, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 16, 2024

Abstract Electrochemically induced, decarboxylative functionalization of chromone‐3‐carboxylic acids by N ‐hydroxyphthalimide esters as alkyl radical precursors was studied. Electrochemical protocol offers a sustainable and green approach, obviating the need for catalysts, relying on direct reduction NHPI using electric current. Developed provides straightforward route to synthesis diverse molecules with potential biological activity.

Язык: Английский

Процитировано

0