Sustainable and scalable one-pot synthesis of diaryliodonium salts

Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Two one-pot syntheses of diaryliodonium triflates are presented, rendering the production these electrophilic arylating agents more sustainable.

Язык: Английский

Hypervalent Iodine-Mediated Selective Monofunctionalization of Calix[4]arenes

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 30, 2025

The selective introduction of a single functionality on the upper rim calix[4]arene is challenging due to identical reactivity its four aryl units. In this study, we introduce novel strategy for monofunctional modification calix[4]arenes using hypervalent iodine-mediated C-H functionalization. This process yields calix[4]arene-iodonium salt, which can be easily isolated distinct solubility compared native calixarene. versatile intermediate efficiently undergoes C-O, C-N, and C-S couplings with variety nucleophiles, including amines, phenols, thiols, sulfinate salts under mild conditions. enables streamlined structural diversification calix[4]arenes, opening new avenues design supramolecular macrocycles tailored functions.

Язык: Английский

Site-Selective Nitration of Arene via Hypervalent Iodine-Mediated C–H Functionalization

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 7, 2025

We developed a novel nitration method using hypervalent iodine for site-selective C-H functionalization. This technique efficiently synthesizes nitroarenes with high regioselectivity and is scalable, enhancing the late-stage modification of bioactive pharmaceuticals.

Язык: Английский