Chinese Journal of Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Май 12, 2025

Comprehensive Summary An efficient photoredox/copper dual‐catalyzed 1,2‐diphosphorothiolation of alkenes with P(O)SH compounds was realized under oxidative conditions. In this transformation, acted as both the phosphorothioate radical source and coupling partner. A wide range valuable vicinal bisphosphorothioates can be easily constructed starting from simple raw materials in a step‐ atom‐economical manner. Notably, reaction system has been successfully used to incorporate two groups into many drug molecules, highlighting substantial synthetic potential protocol.

Язык: Английский