European Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 11, 2025

Abstract We report a temperature‐dependent regiodivergent synthetic strategy for the construction of functionalized maleimides and itaconimides using in‐situ generated pyridinium ylides. This approach enables efficient access to both regioisomeric products under mild straightforward reaction conditions. A variety salts with different aromatic alkyl groups were successfully used N ‐aryl ‐alkyl succinimides demonstrating broad substrate compatibility. The practicality scalability this methodology confirmed through scale‐up experiments, which maintained high yields reproducibility.

Язык: Английский