AgOTf‐Catalysed Regioselective C1‐Amination of Pyrrolo[1,2‐a]quinoxaline With Azodicarboxylates

Applied Organometallic Chemistry, Год журнала: 2025, Номер 39(6)

Опубликована: Май 19, 2025

ABSTRACT AgOTf‐catalysed regioselective C1‐amination of pyrrolo[1,2‐ a ]quinoxaline has been developed. The reaction allowed the use various ]quinoxalines and azodicarboxylates as coupling partners to afford C1‐aminated products with good excellent yields. synthetic strategy showed regioselectivity, functional group tolerance well gram‐scale synthesis. amination were further modified furnish structurally diverse compounds.

Язык: Английский

Photoexcited Copper-Catalyzed Difunctionalization of Alkenes for the Synthesis of 2,5-Diamino Acid Derivatives via Uncommon 1,2-Hydrogen Atom Transfer of Amidyl Radicals

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 25, 2025

Compared with 1,5-hydrogen atom transfer (1,5-HAT) processes, 1,2-HAT processes have been reported less frequently. And, the synthesis of 2,5-diamino acid derivatives via a mild photocatalytic approach has not yet. Herein, we report photoexcited copper-catalyzed difunctionalization alkenes for uncommon 1,2-HAT. The potential synthetic merit this reaction is proven through scale-up reaction. Notably, new protocol successfully applied to obtain series derivatives.

Язык: Английский