Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Апрель 17, 2025

The construction of C-S bonds has garnered significant interest due to the ubiquitous presence organosulfur compounds in natural products and bioactive molecules. Herein, we report a one-pot, stepwise desulfuration strategy employing trisulfides as precursors for synthesis unsymmetrical dialkylthioethers. Our study demonstrates that copper powder facilitates conversion into disulfides, which subsequently undergo nickel-catalyzed reductive coupling afford desired products. This approach provides practical, odorless, broadly applicable method

Язык: Английский