Chinese Journal of Organic Chemistry,
Год журнала:
2022,
Номер
42(10), С. 3051 - 3051
Опубликована: Янв. 1, 2022
Chiral
heterocyclic
compounds
are
an
important
class
of
chiral
substances,
which
widespread
in
many
drugs,
pesticides
and
catalysts.Therefore,
the
efficient
asymmetric
synthesis
these
becomes
a
research
hotspot
organic
synthesis.Transition
metal-catalyzed
cyclization
with
heteroatom-dipole
precursors
is
method
to
construct
frameworks.Among
them,
designed
based
on
transition
allyl
or
propargyl
substitutions
have
been
extensively
studied
past
two
decades
occupied
role
this
field.The
cyclizations
introduced
detail.The
advantages
existing
problems
current
methods
analyzed,
would
provide
useful
reference
for
researchers
related
fields.
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(10), С. 4146 - 4174
Опубликована: Янв. 1, 2022
The
advances
on
metal-catalysed
high-order
dipolar
annulations
were
comprehensively
summarized
in
this
review.
To
further
exploit
the
potential
of
unique
annulation
strategy,
a
research
outlook
was
also
proposed.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
unknown
Опубликована: Май 31, 2024
Bridged
cyclobutanes
and
sulfur
heterocycles
are
currently
under
intense
investigation
as
building
blocks
for
pharmaceutical
drug
design.
Two
formal
cycloaddition
modes
involving
bicyclobutanes
(BCBs)
pyridinium
1,4-zwitterionic
thiolate
derivatives
were
described
to
rapidly
expand
the
chemical
space
of
sulfur-containing
bridged
cyclobutanes.
By
using
Ni(ClO
Chemical Science,
Год журнала:
2020,
Номер
11(11), С. 2888 - 2894
Опубликована: Янв. 1, 2020
Here
we
report
palladium-catalyzed,
regiodivergent
[5
+
4]
and
2]
annulations
of
vinylethylene
carbonates
allylidenemalononitriles
affording
over
50
medium-sized
heterocycles
in
high
isolated
yields
with
excellent
regioselectivities.
Molecules,
Год журнала:
2019,
Номер
24(21), С. 3930 - 3930
Опубликована: Окт. 31, 2019
Functionalized
cyclic
organic
carbonates
and
carbamates
are
frequently
used
in
a
number
of
transition
metal-catalyzed
decarboxylative
reactions
for
the
construction
interesting
molecules.
These
transformations
have
attracted
more
research
attention
recent
years
mainly
due
to
their
advantages
less
waste
generation
versatile
reactivities.
On
basis
previous
reviews
on
this
hot
topic,
present
review
will
focus
development
functionalized
last
two
years.
Chemistry - An Asian Journal,
Год журнала:
2020,
Номер
15(8), С. 1225 - 1233
Опубликована: Фев. 27, 2020
The
spirooxindole
unit
is
one
of
the
most
widely
investigated
compound
skeletons
existing
in
numerous
natural
and
pharmaceutical
molecules.
Thus,
a
large
number
synthetic
methodologies
have
already
been
reported
to
construct
such
core
structure.
trifluoromethyl
group
another
privileged
organic
chemistry.
introduction
CF3
an
framework
can
significantly
improve
properties
molecule.
In
this
context,
efficient
approach
for
construction
trifluoromethyl-containing
spirooxindoles
becomes
promising
research
direction
among
communities
industry
academia.
Minireview,
recent
advances
summarized
discussed.
addition,
representative
corresponding
reaction
mechanisms
described
as
well.
Organic & Biomolecular Chemistry,
Год журнала:
2020,
Номер
18(19), С. 3638 - 3648
Опубликована: Янв. 1, 2020
This
review
provides
an
overview
of
the
palladium-catalysed
diverse
cyclisations
VECs
over
past
five
years,
which
could
offer
powerful
synthetic
tools
to
access
various
functionalised
heterocycles.
Organic Chemistry Frontiers,
Год журнала:
2021,
Номер
8(13), С. 3475 - 3501
Опубликована: Янв. 1, 2021
Carbocyclic
and
heterocyclic
compounds
could
be
constructed
through
the
palladium-catalyzed
annulation
reactions
of
zwitterionic
π-allyl
palladium
or
propargyl
complexes
with
unsaturated
electrophiles.
Abstract
Palladium‐catalyzed
decarboxylative
cycloadditions
have
emerged
as
highly
effective
methods
for
constructing
structurally
diverse
carbo‐
and
heterocycles
because
of
the
formation
at
least
two
carbon‐carbon
or
carbon‐heteroatom
bonds
in
a
single
step.
It
is
great
interest
to
chemists
that
this
type
cycloaddition
reactions
possesses
some
special
advantages
such
high
reactivity,
exclusive
regioselectivity,
good
functional
group
compatibility.
Based
on
these
qualities,
palladium‐catalyzed
present
strong
ability
synthetic
chemistry
been
flourished
especially
last
five
years.
In
review,
achievements
involving
cyclic
carbonates,
carbamates,
lactones
accessing
oxacyclo‐,
azacyclo‐
carbocyclic
compounds
are
addressed.
Mechanistic
insights
applications
toward
synthesis
natural
products
discussed.
The
challenges
opportunities
field
also
outlined.
RSC Advances,
Год журнала:
2021,
Номер
11(13), С. 7146 - 7179
Опубликована: Янв. 1, 2021
Spirooxindoles
are
used
as
anticancer-,
antiviral-,
antimicrobial
agents
etc.
The
use
of
transition
metals
catalysts
for
the
synthesis
spirooxindoles
is
advancing
rapidly.
Here,
we
focus
on
recent
advances
in
metal-catalyzed
spirooxindoles.
